Abstract
Complexation equilibria, in mixed water-methanol solvent media, between native β-cyclodextrin and a set of suitably selected p-nitro-aniline derivatives were studied by means of polarimetry. The effects exerted by the organic co-solvent on the conditional inclusion free energies ΔGcond 0 and the differential molar optical rotations ΔΘ were thoroughly analyzed under the perspective of the enthalpy-entropy compensation effect. Experimental data suggest an intimate participation ('dynamic co-inclusion') of solvent molecules in the formation and in the conformational dynamics of the host-guest inclusion complex.
Lingua originale | English |
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pagine (da-a) | 2037-2042 |
Numero di pagine | 6 |
Rivista | Tetrahedron |
Volume | 65 |
Stato di pubblicazione | Published - 2009 |
All Science Journal Classification (ASJC) codes
- ???subjectarea.asjc.1300.1303???
- ???subjectarea.asjc.3000.3002???
- ???subjectarea.asjc.1600.1605???