Better IQ but worse Premorbid Academic Adjustment in cannabis-users psychotic patients: another brick in the intuition

Risultato della ricerca: Other

Abstract

Purpose: several studies report that patients with psychosis who used cannabis in their lifetime have a better cognitive performance than those who did not and this association is most likely due to a better premorbid functioning. We aimed to test the hypothesis of a better premorbid functioning in First Episode Psychosis (FEP) cannabis-using and non-using patients coming from different European countries. Materials and Methods: 1.745 people (746 cases; 999 healthy controls) completed the assessment for Intellectual Quotient (IQ) (WAIS-brief version) premorbid adjustment (Premorbid Adjustment Scale – PAS) and cannabis use (CEQ-Revised). We first obtained two main factors from PAS: “Premorbid Social Adjustment” (PSA) and “Premorbid Academic Adjustment” (PAA). We therefore performed linear mixed models with IQ, PSA, and PAA as dependent variables and cannabis lifetime (Yes/No) and subject status (Cases/Controls) as independent variables. Results: across all countries, IQ was higher in cannabis users patients compared to non users (p=0.027). Conversely, PAA resulted worst in cannabis-users patients than non users (p<0.001). Neverthless, cannabis-users patients showed better PSA scores than non users (p=0.009) and this difference was significantly greater in patients than controls (p=0.038). Moreover, a better IQ resulted related to a better PAA (<0.001) but not to PSA (p=0.260). Conclusions: a better IQ is not directly predictable by a better adjustment at school between 12 and 16 years (PAA), even if these two scores are positivelty correlated. Additionally we can speculate an independent relationship of IQ and a better sociability between 12 and 16 years (PSA) with cannabis use.
Lingua originaleEnglish
Pagine37-37
Numero di pagine1
Stato di pubblicazionePublished - 2016

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Social Adjustment
Intuition
Cannabis
Psychotic Disorders

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@conference{54f07ee478874ea9b733a5be2c577f2d,
title = "Better IQ but worse Premorbid Academic Adjustment in cannabis-users psychotic patients: another brick in the intuition",
abstract = "Purpose: several studies report that patients with psychosis who used cannabis in their lifetime have a better cognitive performance than those who did not and this association is most likely due to a better premorbid functioning. We aimed to test the hypothesis of a better premorbid functioning in First Episode Psychosis (FEP) cannabis-using and non-using patients coming from different European countries. Materials and Methods: 1.745 people (746 cases; 999 healthy controls) completed the assessment for Intellectual Quotient (IQ) (WAIS-brief version) premorbid adjustment (Premorbid Adjustment Scale – PAS) and cannabis use (CEQ-Revised). We first obtained two main factors from PAS: “Premorbid Social Adjustment” (PSA) and “Premorbid Academic Adjustment” (PAA). We therefore performed linear mixed models with IQ, PSA, and PAA as dependent variables and cannabis lifetime (Yes/No) and subject status (Cases/Controls) as independent variables. Results: across all countries, IQ was higher in cannabis users patients compared to non users (p=0.027). Conversely, PAA resulted worst in cannabis-users patients than non users (p<0.001). Neverthless, cannabis-users patients showed better PSA scores than non users (p=0.009) and this difference was significantly greater in patients than controls (p=0.038). Moreover, a better IQ resulted related to a better PAA (<0.001) but not to PSA (p=0.260). Conclusions: a better IQ is not directly predictable by a better adjustment at school between 12 and 16 years (PAA), even if these two scores are positivelty correlated. Additionally we can speculate an independent relationship of IQ and a better sociability between 12 and 16 years (PSA) with cannabis use.",
author = "{La Barbera}, Daniele and Laura Ferraro and {La Cascia}, Caterina and Fabio Seminerio and Veronica Capuccio and Alice Mul{\`e} and Lucia Sideli",
year = "2016",
language = "English",
pages = "37--37",

}

TY - CONF

T1 - Better IQ but worse Premorbid Academic Adjustment in cannabis-users psychotic patients: another brick in the intuition

AU - La Barbera, Daniele

AU - Ferraro, Laura

AU - La Cascia, Caterina

AU - Seminerio, Fabio

AU - Capuccio, Veronica

AU - Mulè, Alice

AU - Sideli, Lucia

PY - 2016

Y1 - 2016

N2 - Purpose: several studies report that patients with psychosis who used cannabis in their lifetime have a better cognitive performance than those who did not and this association is most likely due to a better premorbid functioning. We aimed to test the hypothesis of a better premorbid functioning in First Episode Psychosis (FEP) cannabis-using and non-using patients coming from different European countries. Materials and Methods: 1.745 people (746 cases; 999 healthy controls) completed the assessment for Intellectual Quotient (IQ) (WAIS-brief version) premorbid adjustment (Premorbid Adjustment Scale – PAS) and cannabis use (CEQ-Revised). We first obtained two main factors from PAS: “Premorbid Social Adjustment” (PSA) and “Premorbid Academic Adjustment” (PAA). We therefore performed linear mixed models with IQ, PSA, and PAA as dependent variables and cannabis lifetime (Yes/No) and subject status (Cases/Controls) as independent variables. Results: across all countries, IQ was higher in cannabis users patients compared to non users (p=0.027). Conversely, PAA resulted worst in cannabis-users patients than non users (p<0.001). Neverthless, cannabis-users patients showed better PSA scores than non users (p=0.009) and this difference was significantly greater in patients than controls (p=0.038). Moreover, a better IQ resulted related to a better PAA (<0.001) but not to PSA (p=0.260). Conclusions: a better IQ is not directly predictable by a better adjustment at school between 12 and 16 years (PAA), even if these two scores are positivelty correlated. Additionally we can speculate an independent relationship of IQ and a better sociability between 12 and 16 years (PSA) with cannabis use.

AB - Purpose: several studies report that patients with psychosis who used cannabis in their lifetime have a better cognitive performance than those who did not and this association is most likely due to a better premorbid functioning. We aimed to test the hypothesis of a better premorbid functioning in First Episode Psychosis (FEP) cannabis-using and non-using patients coming from different European countries. Materials and Methods: 1.745 people (746 cases; 999 healthy controls) completed the assessment for Intellectual Quotient (IQ) (WAIS-brief version) premorbid adjustment (Premorbid Adjustment Scale – PAS) and cannabis use (CEQ-Revised). We first obtained two main factors from PAS: “Premorbid Social Adjustment” (PSA) and “Premorbid Academic Adjustment” (PAA). We therefore performed linear mixed models with IQ, PSA, and PAA as dependent variables and cannabis lifetime (Yes/No) and subject status (Cases/Controls) as independent variables. Results: across all countries, IQ was higher in cannabis users patients compared to non users (p=0.027). Conversely, PAA resulted worst in cannabis-users patients than non users (p<0.001). Neverthless, cannabis-users patients showed better PSA scores than non users (p=0.009) and this difference was significantly greater in patients than controls (p=0.038). Moreover, a better IQ resulted related to a better PAA (<0.001) but not to PSA (p=0.260). Conclusions: a better IQ is not directly predictable by a better adjustment at school between 12 and 16 years (PAA), even if these two scores are positivelty correlated. Additionally we can speculate an independent relationship of IQ and a better sociability between 12 and 16 years (PSA) with cannabis use.

UR - http://hdl.handle.net/10447/206734

UR - http://onlinelibrary.wiley.com/doi/10.1111/eip.12395/full

M3 - Other

SP - 37

EP - 37

ER -