Benign and severe early-life seizures: a round in the first year of life.

Giovanni Corsello, Martino Ruggieri, Silvia Marino, Piero Pavone, Simona Marino, Simona Marino, Simona Marino, Raffaele Falsaperla, Piero Pavone, Raffaele Falsaperla

Risultato della ricerca: Articlepeer review

4 Citazioni (Scopus)

Abstract

At the onset, differentiation between abnormal non-epileptic movements, and epileptic seizures presenting in early life is difficult as is clinical diagnosis and prognostic evaluation of the various seizure disorders presenting at this age. Seizures starting in the first year of life including the neonatal period might have a favorable course, such as in infants presenting with benign familial neonatal epilepsy, febrile seizures simplex or acute symptomatic seizures. However, in some cases, the onset of seizures at birth or in the first months of life have a dramatic evolution with severe cerebral impairment. Seizure disorders starting in early life include the "epileptic encephalopathies", a group of conditions characterized by drug resistant seizures, delayed developmental skills, and intellective disability. This group of disorders includes early infantile epileptic encephalopathy also known as Ohtahara syndrome, early myoclonic encephalopathy, epilepsy of infancy with migrating focal seizures, infantile spasms syndrome (also known as West syndrome), severe myoclonic epilepsy in infancy (also known as Dravet syndrome) and, myoclonic encephalopathies in non-progressive disorder. Here we report on seizures manifesting in the first year of life including the neonatal period. Conditions with a benign course, and those with severe evolution are presented. At this early age, clinical identification of seizures, distinction of each of these disorders, type of treatment and prognosis is particularly challenging. The aim of this report is to present the clinical manifestations of each of these disorders and provide an updated review of the conditions associated with seizures in the first year of life.
Lingua originaleEnglish
pagine (da-a)54-64
Numero di pagine11
RivistaTHE ITALIAN JOURNAL OF PEDIATRICS
Volume44
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

Fingerprint Entra nei temi di ricerca di 'Benign and severe early-life seizures: a round in the first year of life.'. Insieme formano una fingerprint unica.

Cita questo