TY - JOUR
T1 - Avoiding Pitfalls in the Interpretation of Gadoxetic Acid–Enhanced Magnetic Resonance Imaging
AU - Brancatelli, Giuseppe
AU - Ronot, Maxime
AU - Terraz, Sylvain
AU - Dioguardi Burgio, Marco
AU - Paulatto, Luisa
AU - Vilgrain, Valérie
PY - 2016
Y1 - 2016
N2 - Gadoxetic acid is extensively used in the following 3 main clinical situations: characterization of small nodules in patients with cirrhosis, preoperative staging of liver metastases, and characterization of incidentally discovered focal liver lesions. Owing to the rapid entry of gadoxetic acid into hepatocytes, the traditional features of liver tumors are modified on magnetic resonance (MR) imaging, especially during delayed phase sequences. Thus, although the added value of gadoxetic acid for the detection and characterization of focal liver lesions is now clear, its unique pharmacokinetics as well as the presence of mimicking and atypical lesions may lead to misdiagnoses. The goal of this article is to illustrate common and uncommon pitfalls associated with the use of gadoxetic acid–enhanced MR imaging. Moreover, additional MR imaging features that can help establish a correct diagnosis are described.
AB - Gadoxetic acid is extensively used in the following 3 main clinical situations: characterization of small nodules in patients with cirrhosis, preoperative staging of liver metastases, and characterization of incidentally discovered focal liver lesions. Owing to the rapid entry of gadoxetic acid into hepatocytes, the traditional features of liver tumors are modified on magnetic resonance (MR) imaging, especially during delayed phase sequences. Thus, although the added value of gadoxetic acid for the detection and characterization of focal liver lesions is now clear, its unique pharmacokinetics as well as the presence of mimicking and atypical lesions may lead to misdiagnoses. The goal of this article is to illustrate common and uncommon pitfalls associated with the use of gadoxetic acid–enhanced MR imaging. Moreover, additional MR imaging features that can help establish a correct diagnosis are described.
KW - Computer-Assisted; Liver Diseases; Magnetic Resonance Imaging; Sensitivity and Specificity; Gadolinium DTPA; Radiology
KW - Contrast Media; Humans; Image Interpretation
KW - Nuclear Medicine and Imaging
KW - Computer-Assisted; Liver Diseases; Magnetic Resonance Imaging; Sensitivity and Specificity; Gadolinium DTPA; Radiology
KW - Contrast Media; Humans; Image Interpretation
KW - Nuclear Medicine and Imaging
UR - http://hdl.handle.net/10447/225719
UR - http://www.elsevier.com/inca/publications/store/6/2/3/1/9/2/index.htt
M3 - Article
VL - 37
SP - 561
EP - 572
JO - Seminars in Ultrasound, CT and MRI
JF - Seminars in Ultrasound, CT and MRI
SN - 0887-2171
ER -