Asymptomatic carotid lesions add to cardiovascular risk prediction

Salvatore Novo, Giuseppina Novo, Ida Maria Muratori, Gisella Rita Amoroso, Luciana D'Angelo, Claudia Luisa Visconti, Egle Corrado, Monica Lunetta, Rosalba Tantillo, Egle Corrado, Ida Muratori, Gisella R. Amoroso, Claudia L. Visconti, Luciana D'Angelo, Monica Lunetta, Giovanni Fazio, Salvatore Novo, Giuseppina Novo

Risultato della ricerca: Article

22 Citazioni (Scopus)

Abstract

To show that subclinical atherosclerosis (subclinical-ATS) of carotid arteries [intima–media thickness (IMT) or asymptomatic carotid plaque (ACP)], may provide additional information for risk stratification, in asymptomatic patients, aged greater than 45 years, with a cluster of risk factors (RFs). We studied 558 asymptomatic patients (235 males). RFs for atherosclerosis were assessed and the 10-year-risk was calculated according to the Italian risk score. Doppler ultrasound of carotid arteries identified the presence of IMT greater than 0.9 mm in 183 patients and ACP in 147 patients. One hundred and fifty-three patients developed cerebrovascular or cardiovascular (CV) events in the follow-up: 67 developed acute myocardial infarction, 39 developed angina, 25 had a stroke or transient ischemic attack, six died for CV events, and 16 underwent percutaneous or surgical revascularization. The incidence reflected the different risk profiles (4,14, and 20%, respectively). However, in patients with baseline subclinical-ATS the incidence of events increased to 35, 46, and 63%, respectively. In the multivariate analysis the incidence of events was significantly influenced by the presence of asymptomatic carotid lesions in each risk category. In our experience, the incidence of CV events is enhanced in patients with subclinical-ATS. Increased IMT and ACP predict CV events and improve the risk stratification of asymptomatic patients aged greater than 45 years and with a cluster of RFs, in a long-term follow-up
Lingua originaleEnglish
pagine (da-a)514-518
Numero di pagine5
RivistaEUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION
Volume17
Stato di pubblicazionePublished - 2010

Fingerprint

Atherosclerosis
Incidence
Carotid Arteries
Doppler Ultrasonography
Transient Ischemic Attack
Multivariate Analysis
Stroke
Myocardial Infarction

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Cardiology and Cardiovascular Medicine

Cita questo

Asymptomatic carotid lesions add to cardiovascular risk prediction. / Novo, Salvatore; Novo, Giuseppina; Muratori, Ida Maria; Amoroso, Gisella Rita; D'Angelo, Luciana; Visconti, Claudia Luisa; Corrado, Egle; Lunetta, Monica; Tantillo, Rosalba; Corrado, Egle; Muratori, Ida; Amoroso, Gisella R.; Visconti, Claudia L.; D'Angelo, Luciana; Lunetta, Monica; Fazio, Giovanni; Novo, Salvatore; Novo, Giuseppina.

In: EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION, Vol. 17, 2010, pag. 514-518.

Risultato della ricerca: Article

Novo, S, Novo, G, Muratori, IM, Amoroso, GR, D'Angelo, L, Visconti, CL, Corrado, E, Lunetta, M, Tantillo, R, Corrado, E, Muratori, I, Amoroso, GR, Visconti, CL, D'Angelo, L, Lunetta, M, Fazio, G, Novo, S & Novo, G 2010, 'Asymptomatic carotid lesions add to cardiovascular risk prediction', EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION, vol. 17, pagg. 514-518.
Novo, Salvatore ; Novo, Giuseppina ; Muratori, Ida Maria ; Amoroso, Gisella Rita ; D'Angelo, Luciana ; Visconti, Claudia Luisa ; Corrado, Egle ; Lunetta, Monica ; Tantillo, Rosalba ; Corrado, Egle ; Muratori, Ida ; Amoroso, Gisella R. ; Visconti, Claudia L. ; D'Angelo, Luciana ; Lunetta, Monica ; Fazio, Giovanni ; Novo, Salvatore ; Novo, Giuseppina. / Asymptomatic carotid lesions add to cardiovascular risk prediction. In: EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION. 2010 ; Vol. 17. pagg. 514-518.
@article{7b7f2967554b4d59aa56e9581de11bde,
title = "Asymptomatic carotid lesions add to cardiovascular risk prediction",
abstract = "To show that subclinical atherosclerosis (subclinical-ATS) of carotid arteries [intima–media thickness (IMT) or asymptomatic carotid plaque (ACP)], may provide additional information for risk stratification, in asymptomatic patients, aged greater than 45 years, with a cluster of risk factors (RFs). We studied 558 asymptomatic patients (235 males). RFs for atherosclerosis were assessed and the 10-year-risk was calculated according to the Italian risk score. Doppler ultrasound of carotid arteries identified the presence of IMT greater than 0.9 mm in 183 patients and ACP in 147 patients. One hundred and fifty-three patients developed cerebrovascular or cardiovascular (CV) events in the follow-up: 67 developed acute myocardial infarction, 39 developed angina, 25 had a stroke or transient ischemic attack, six died for CV events, and 16 underwent percutaneous or surgical revascularization. The incidence reflected the different risk profiles (4,14, and 20{\%}, respectively). However, in patients with baseline subclinical-ATS the incidence of events increased to 35, 46, and 63{\%}, respectively. In the multivariate analysis the incidence of events was significantly influenced by the presence of asymptomatic carotid lesions in each risk category. In our experience, the incidence of CV events is enhanced in patients with subclinical-ATS. Increased IMT and ACP predict CV events and improve the risk stratification of asymptomatic patients aged greater than 45 years and with a cluster of RFs, in a long-term follow-up",
author = "Salvatore Novo and Giuseppina Novo and Muratori, {Ida Maria} and Amoroso, {Gisella Rita} and Luciana D'Angelo and Visconti, {Claudia Luisa} and Egle Corrado and Monica Lunetta and Rosalba Tantillo and Egle Corrado and Ida Muratori and Amoroso, {Gisella R.} and Visconti, {Claudia L.} and Luciana D'Angelo and Monica Lunetta and Giovanni Fazio and Salvatore Novo and Giuseppina Novo",
year = "2010",
language = "English",
volume = "17",
pages = "514--518",
journal = "European Journal of Cardiovascular Prevention and Rehabilitation",
issn = "1741-8267",
publisher = "Sage Publications",

}

TY - JOUR

T1 - Asymptomatic carotid lesions add to cardiovascular risk prediction

AU - Novo, Salvatore

AU - Novo, Giuseppina

AU - Muratori, Ida Maria

AU - Amoroso, Gisella Rita

AU - D'Angelo, Luciana

AU - Visconti, Claudia Luisa

AU - Corrado, Egle

AU - Lunetta, Monica

AU - Tantillo, Rosalba

AU - Corrado, Egle

AU - Muratori, Ida

AU - Amoroso, Gisella R.

AU - Visconti, Claudia L.

AU - D'Angelo, Luciana

AU - Lunetta, Monica

AU - Fazio, Giovanni

AU - Novo, Salvatore

AU - Novo, Giuseppina

PY - 2010

Y1 - 2010

N2 - To show that subclinical atherosclerosis (subclinical-ATS) of carotid arteries [intima–media thickness (IMT) or asymptomatic carotid plaque (ACP)], may provide additional information for risk stratification, in asymptomatic patients, aged greater than 45 years, with a cluster of risk factors (RFs). We studied 558 asymptomatic patients (235 males). RFs for atherosclerosis were assessed and the 10-year-risk was calculated according to the Italian risk score. Doppler ultrasound of carotid arteries identified the presence of IMT greater than 0.9 mm in 183 patients and ACP in 147 patients. One hundred and fifty-three patients developed cerebrovascular or cardiovascular (CV) events in the follow-up: 67 developed acute myocardial infarction, 39 developed angina, 25 had a stroke or transient ischemic attack, six died for CV events, and 16 underwent percutaneous or surgical revascularization. The incidence reflected the different risk profiles (4,14, and 20%, respectively). However, in patients with baseline subclinical-ATS the incidence of events increased to 35, 46, and 63%, respectively. In the multivariate analysis the incidence of events was significantly influenced by the presence of asymptomatic carotid lesions in each risk category. In our experience, the incidence of CV events is enhanced in patients with subclinical-ATS. Increased IMT and ACP predict CV events and improve the risk stratification of asymptomatic patients aged greater than 45 years and with a cluster of RFs, in a long-term follow-up

AB - To show that subclinical atherosclerosis (subclinical-ATS) of carotid arteries [intima–media thickness (IMT) or asymptomatic carotid plaque (ACP)], may provide additional information for risk stratification, in asymptomatic patients, aged greater than 45 years, with a cluster of risk factors (RFs). We studied 558 asymptomatic patients (235 males). RFs for atherosclerosis were assessed and the 10-year-risk was calculated according to the Italian risk score. Doppler ultrasound of carotid arteries identified the presence of IMT greater than 0.9 mm in 183 patients and ACP in 147 patients. One hundred and fifty-three patients developed cerebrovascular or cardiovascular (CV) events in the follow-up: 67 developed acute myocardial infarction, 39 developed angina, 25 had a stroke or transient ischemic attack, six died for CV events, and 16 underwent percutaneous or surgical revascularization. The incidence reflected the different risk profiles (4,14, and 20%, respectively). However, in patients with baseline subclinical-ATS the incidence of events increased to 35, 46, and 63%, respectively. In the multivariate analysis the incidence of events was significantly influenced by the presence of asymptomatic carotid lesions in each risk category. In our experience, the incidence of CV events is enhanced in patients with subclinical-ATS. Increased IMT and ACP predict CV events and improve the risk stratification of asymptomatic patients aged greater than 45 years and with a cluster of RFs, in a long-term follow-up

UR - http://hdl.handle.net/10447/58115

M3 - Article

VL - 17

SP - 514

EP - 518

JO - European Journal of Cardiovascular Prevention and Rehabilitation

JF - European Journal of Cardiovascular Prevention and Rehabilitation

SN - 1741-8267

ER -