Association of renal resistive index with aortic pulse wave velocity in hypertensive patients.

Mulè, G; D’Ignoto, F

Risultato della ricerca: Article

21 Citazioni (Scopus)

Abstract

Background: Recent data suggest that renal haemodynamic parameters obtained by duplex Doppler sonography, especially the intrarenal resistive index (RI), may be associated with systemic vascular changes. However, conflicting data exist about the independent relationship between aortic stiffness and RI. The aim of this study was to evaluate the relationship between RI and arterial stiffness, assessed by aortic pulse wave velocity (aPWV), in hypertensive patients. Design: Cross-sectional study. Methods: We enrolled 264 hypertensive subjects aged between 30 and 70 years. They were divided into two groups, either with normal renal function (n=140) or with chronic kidney disease (CKD) (n=124). Each patient underwent assessment of ultrasonographic renal RI and measurement of aPWV through oscillometric device. Results: Patients with renal RI>0.7 showed higher values of aPWV, both in the overall population (p<0.001) and in the subgroups with (p<0.01) and without CKD (p<0.01). Moreover, statistically significant correlations were observed between aPWV and RI in the whole population (r=0.38, p<0.001) and in the subgroups with (r=0.35, p<0.001) and without CKD (r=0.31, p<0.001). These correlations held even after adjustment for several confounding factors in multivariate analyses. Conclusions: Our results seem to corroborate the concept that the RI may be considered as a marker of systemic vascular changes and therefore a predictor of cardiovascular risk.
Lingua originaleEnglish
pagine (da-a)415-422
Numero di pagine8
RivistaEuropean Journal of Preventive Cardiology
Volume22
Stato di pubblicazionePublished - 2015

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Pulse Wave Analysis
Chronic Renal Insufficiency
Kidney
Vascular Stiffness
Blood Vessels
Doppler Duplex Ultrasonography
Population
Multivariate Analysis
Cross-Sectional Studies
Hemodynamics
Equipment and Supplies

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)
  • Epidemiology

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Association of renal resistive index with aortic pulse wave velocity in hypertensive patients. / Mulè, G; D’Ignoto, F.

In: European Journal of Preventive Cardiology, Vol. 22, 2015, pag. 415-422.

Risultato della ricerca: Article

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title = "Association of renal resistive index with aortic pulse wave velocity in hypertensive patients.",
abstract = "Background: Recent data suggest that renal haemodynamic parameters obtained by duplex Doppler sonography, especially the intrarenal resistive index (RI), may be associated with systemic vascular changes. However, conflicting data exist about the independent relationship between aortic stiffness and RI. The aim of this study was to evaluate the relationship between RI and arterial stiffness, assessed by aortic pulse wave velocity (aPWV), in hypertensive patients. Design: Cross-sectional study. Methods: We enrolled 264 hypertensive subjects aged between 30 and 70 years. They were divided into two groups, either with normal renal function (n=140) or with chronic kidney disease (CKD) (n=124). Each patient underwent assessment of ultrasonographic renal RI and measurement of aPWV through oscillometric device. Results: Patients with renal RI>0.7 showed higher values of aPWV, both in the overall population (p<0.001) and in the subgroups with (p<0.01) and without CKD (p<0.01). Moreover, statistically significant correlations were observed between aPWV and RI in the whole population (r=0.38, p<0.001) and in the subgroups with (r=0.35, p<0.001) and without CKD (r=0.31, p<0.001). These correlations held even after adjustment for several confounding factors in multivariate analyses. Conclusions: Our results seem to corroborate the concept that the RI may be considered as a marker of systemic vascular changes and therefore a predictor of cardiovascular risk.",
author = "{Mul{\`e}, G; D’Ignoto, F} and Santina Cottone and Giuseppe Mule' and Calogero Geraci and Foraci, {Anna Carola} and Manuela Mogavero and Massimiliano Morreale and Giulio Geraci and Francesco D'Ignoto",
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T1 - Association of renal resistive index with aortic pulse wave velocity in hypertensive patients.

AU - Mulè, G; D’Ignoto, F

AU - Cottone, Santina

AU - Mule', Giuseppe

AU - Geraci, Calogero

AU - Foraci, Anna Carola

AU - Mogavero, Manuela

AU - Morreale, Massimiliano

AU - Geraci, Giulio

AU - D'Ignoto, Francesco

PY - 2015

Y1 - 2015

N2 - Background: Recent data suggest that renal haemodynamic parameters obtained by duplex Doppler sonography, especially the intrarenal resistive index (RI), may be associated with systemic vascular changes. However, conflicting data exist about the independent relationship between aortic stiffness and RI. The aim of this study was to evaluate the relationship between RI and arterial stiffness, assessed by aortic pulse wave velocity (aPWV), in hypertensive patients. Design: Cross-sectional study. Methods: We enrolled 264 hypertensive subjects aged between 30 and 70 years. They were divided into two groups, either with normal renal function (n=140) or with chronic kidney disease (CKD) (n=124). Each patient underwent assessment of ultrasonographic renal RI and measurement of aPWV through oscillometric device. Results: Patients with renal RI>0.7 showed higher values of aPWV, both in the overall population (p<0.001) and in the subgroups with (p<0.01) and without CKD (p<0.01). Moreover, statistically significant correlations were observed between aPWV and RI in the whole population (r=0.38, p<0.001) and in the subgroups with (r=0.35, p<0.001) and without CKD (r=0.31, p<0.001). These correlations held even after adjustment for several confounding factors in multivariate analyses. Conclusions: Our results seem to corroborate the concept that the RI may be considered as a marker of systemic vascular changes and therefore a predictor of cardiovascular risk.

AB - Background: Recent data suggest that renal haemodynamic parameters obtained by duplex Doppler sonography, especially the intrarenal resistive index (RI), may be associated with systemic vascular changes. However, conflicting data exist about the independent relationship between aortic stiffness and RI. The aim of this study was to evaluate the relationship between RI and arterial stiffness, assessed by aortic pulse wave velocity (aPWV), in hypertensive patients. Design: Cross-sectional study. Methods: We enrolled 264 hypertensive subjects aged between 30 and 70 years. They were divided into two groups, either with normal renal function (n=140) or with chronic kidney disease (CKD) (n=124). Each patient underwent assessment of ultrasonographic renal RI and measurement of aPWV through oscillometric device. Results: Patients with renal RI>0.7 showed higher values of aPWV, both in the overall population (p<0.001) and in the subgroups with (p<0.01) and without CKD (p<0.01). Moreover, statistically significant correlations were observed between aPWV and RI in the whole population (r=0.38, p<0.001) and in the subgroups with (r=0.35, p<0.001) and without CKD (r=0.31, p<0.001). These correlations held even after adjustment for several confounding factors in multivariate analyses. Conclusions: Our results seem to corroborate the concept that the RI may be considered as a marker of systemic vascular changes and therefore a predictor of cardiovascular risk.

UR - http://hdl.handle.net/10447/92484

UR - http://cpr.sagepub.com/content/early/2014/02/11/2047487314524683.full

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JO - European Journal of Preventive Cardiology

JF - European Journal of Preventive Cardiology

SN - 2047-4873

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