Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients with Non-alcoholic Fatty Liver Disease

Risultato della ricerca: Article

8 Citazioni (Scopus)

Abstract

Patients with nonalcoholic fatty liver disease (NAFLD) have an increased risk for liver-related complications, such as decompensation, hepatocellular carcinoma (HCC), and death; the severity of liver fibrosis and metabolic comorbidities are the main risk factors. A single nucleotide polymorphism in patatin-like phospholipase domain-containing-3 (PNPLA3) gene is associated with higher prevalence of liver damage and HCC, but there are no data from prospective studies of outcomes of patients with this polymorphism. We investigated whether the common rs738409 variant in PNPLA3 gene associates with the occurrence of liver-related events and death in a large cohort of patients with NAFLD.
Lingua originaleEnglish
Numero di pagine12
RivistaClinical Gastroenterology and Hepatology
Stato di pubblicazionePublished - 2019

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Fingerprint Entra nei temi di ricerca di 'Association Between PNPLA3 rs738409 C>G Variant and Liver-Related Outcomes in Patients with Non-alcoholic Fatty Liver Disease'. Insieme formano una fingerprint unica.

  • Cita questo