TY - JOUR
T1 - Assessment of no-reflow phenomenon by myocardial blush grade and pulsed wave tissue doppler imaging in patients with acute coronary syndrome
AU - Novo, Salvatore
AU - Evola, Salvatore
AU - Novo, Giuseppina
AU - Assennato, Pasquale
AU - Triolo, Oreste Fabio
AU - Triolo, Oreste Fabio
AU - Novo, Salvatore
AU - Giambanco, Salvatore
AU - Sutera, Maria Rita
AU - Arvigo, Luisa
AU - Fata, Benedetta La
AU - Galifi, Maria Ausilia
AU - Novo, Giuseppina
AU - Lisi, Daniela Di
AU - Evola, Salvatore
AU - Assennato, Pasquale
AU - Arvigo, Luisa
PY - 2014
Y1 - 2014
N2 - Background: No-reflow phenomenon is a complication of myocardial revascularization and it is associated with a worse prognosis. Materials and Methods: A prospective study was carried out enrolling patients with acute myocardial infarction (64 patients, 49 male and 15 female, median age 64.9 ± 10.61 years), both STEMI and NSTEMI, who underwent myocardial revascularization with percutaneous coronary intervention (PCI). TIMI flow and Myocardial Blush Grade (MBG) were assessed at baseline (T0), in addition to tissue Doppler imaging (TDI) and electrocardiogram. Cardiological evaluation was also performed at T1 (one month after PCI) and T2 (every year after revascularization for a mean follow-up of 24.9 months ± 6.93 months). Patients were divided into two groups on the basis of MBG. Results: In the present study, we found at T1 a significant association between MBG and dyslipidemia (P = 0,038) and NYHA class and MBG (P = 0,040), among clinical variables and cardiovascular risk factors. Moreover, a statistically significant relationship was observed between MBG and a new echocardiographic index of systolic and diastolic dysfunction, the EAS index measured with tissue Doppler imaging (P = 0,013). At T2, the EAS parameter was also significantly impaired in patients with reduced MBG, compared to patients with normal MBG (P = 0,003). Conclusions: This study demonstrates that the combined evaluation of systolic and diastolic dysfunction by EAS index, according to the literature, could detect a subclinical ventricular dysfunction due to a perfusion defect. Therefore, EAS index could be a useful parameter to be measured in the follow-up of patients undergoing revascularization. © 2014 Journal of Cardiovascular Echography. All right Reserved.
AB - Background: No-reflow phenomenon is a complication of myocardial revascularization and it is associated with a worse prognosis. Materials and Methods: A prospective study was carried out enrolling patients with acute myocardial infarction (64 patients, 49 male and 15 female, median age 64.9 ± 10.61 years), both STEMI and NSTEMI, who underwent myocardial revascularization with percutaneous coronary intervention (PCI). TIMI flow and Myocardial Blush Grade (MBG) were assessed at baseline (T0), in addition to tissue Doppler imaging (TDI) and electrocardiogram. Cardiological evaluation was also performed at T1 (one month after PCI) and T2 (every year after revascularization for a mean follow-up of 24.9 months ± 6.93 months). Patients were divided into two groups on the basis of MBG. Results: In the present study, we found at T1 a significant association between MBG and dyslipidemia (P = 0,038) and NYHA class and MBG (P = 0,040), among clinical variables and cardiovascular risk factors. Moreover, a statistically significant relationship was observed between MBG and a new echocardiographic index of systolic and diastolic dysfunction, the EAS index measured with tissue Doppler imaging (P = 0,013). At T2, the EAS parameter was also significantly impaired in patients with reduced MBG, compared to patients with normal MBG (P = 0,003). Conclusions: This study demonstrates that the combined evaluation of systolic and diastolic dysfunction by EAS index, according to the literature, could detect a subclinical ventricular dysfunction due to a perfusion defect. Therefore, EAS index could be a useful parameter to be measured in the follow-up of patients undergoing revascularization. © 2014 Journal of Cardiovascular Echography. All right Reserved.
KW - Acute myocardial infarction; myocardial blush grade; myocardial perfusion; no reflow; tissue doppler imaging; Cardiology and Cardiovascular Medicine; Radiology
KW - Nuclear Medicine and Imaging
KW - Acute myocardial infarction; myocardial blush grade; myocardial perfusion; no reflow; tissue doppler imaging; Cardiology and Cardiovascular Medicine; Radiology
KW - Nuclear Medicine and Imaging
UR - http://hdl.handle.net/10447/215045
UR - http://www.jcecho.org/backissues.asp
M3 - Article
VL - 24
SP - 52
EP - 56
JO - JOURNAL OF CARDIOVASCULAR ECHOGRAPHY
JF - JOURNAL OF CARDIOVASCULAR ECHOGRAPHY
SN - 2211-4122
ER -