Assessment of genetically modified maize 4114 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2014-123)

Barbara Rosy Ines Manachini, Barbara Manachini, Yann Devos, Jose Ángel Gómez Ruiz, Jeremy Sweet, Huw Jones, Anna Lanzoni, Elsa Ebbesen Nielsen, Huw Jones, Fabien Nogué, Michele Ardizzone, Fernando Àlvarez, Jose Ángel Gómez Ruiz, Antonio Fernandez Dumont, Philippe Guerche, Nikoletta Papadopoulou, Irina Olaru, Franco Maria Neri, Konstantinos Paraskevopoulos, Christophe RobagliaAndrew Nicholas Birch, Mikołaj Antoni Gralak, Adinda De Schrijver, Nils Rostoks, Josep Casacuberta, Fabien Nogué, Antoine Messéan, Christoph Tebbe, Andrew Nicholas Birch, Hermann Broll, Hanspeter Naegeli, Francesco Visioli, Jean-Michel Wal

Risultato della ricerca: Articlepeer review

Abstract

Maize 4114 was developed through Agrobacterium tumefaciens-mediated transformation to provide protection against certain lepidopteran and coleopteran pests by expression of the Cry1F, Cry34Ab1 and Cry35Ab1 proteins derived from Bacillus thuringiensis, and tolerance to the herbicidal active ingredient glufosinate-ammonium by expression of the PAT protein derived from Streptomyces viridochromogenes. The molecular characterisation data did not identify issues requiring assessment for food/feed safety. None of the compositional, agronomic and phenotypic differences identified between maize 4114 and the non-genetically modified (GM) comparator(s) required further assessment. There were no concerns regarding the potential toxicity and allergenicity of the newly expressed proteins Cry1F, Cry34Ab1, Cry35Ab1 and PAT, and no evidence that the genetic modification might significantly change the overall allergenicity of maize 4114. The nutritional value of food/feed derived from maize 4114 is not expected to differ from that derived from non-GM maize varieties and no post-market monitoring of food/feed is considered necessary. In the case of accidental release of viable maize 4114 grains into the environment, maize 4114 would not raise environmental safety concerns. The post-market environmental monitoring plan and reporting intervals are in line with the intended uses of maize 4114. The genetically modified organism (GMO) Panel concludes that maize 4114 is as safe as the non-GM comparator(s) and non-GM reference varieties with respect to potential effects on human and animal health and the environment in the context of the scope of this application.
Lingua originaleEnglish
pagine (da-a)1-25
Numero di pagine25
RivistaTHE EFSA JOURNAL
Volume16
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Food Science
  • Microbiology
  • Animal Science and Zoology
  • veterinary (miscalleneous)
  • Plant Science

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