Antiproliferative Oleanane Saponins from Meryta denhamii

Fabio Venturella, Francesco De Simone, Nunziatina De Tommasi, Francesco De Simone, Fabrizio Dal Piaz, Paolo De Caprariis, Giuseppina Cioffi, Antonio Vassallo, Antonio Vassallo

Risultato della ricerca: Article

16 Citazioni (Scopus)

Abstract

Eight new oleanane saponins (1- 8) together with four know saponins (9-12) were isolated from the aerial parts of Meryta denhamii. Their structures were elucidated by 1D and 2D NMR experiments including 1D TOCSY, DQF-COSY, ROESY, HSQC, and HMBC spectroscopy, as well as ESIMS analysis. The antiproliferative activity of all compounds was evaluated using three murine and human cancer cell lines: J774.A1, HEK-293, and WEHI-164.
Lingua originaleEnglish
pagine (da-a)1000-1004
Numero di pagine4
RivistaJournal of Natural Products
Volume71
Stato di pubblicazionePublished - 2008

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

Fingerprint Entra nei temi di ricerca di 'Antiproliferative Oleanane Saponins from Meryta denhamii'. Insieme formano una fingerprint unica.

Cita questo