Antimicrobial additives for poly(lactic acid) materials and their applications: current state and perspectives

Roberto Scaffaro, Francesco Lopresti, Antonia Nostro, Andreana Marino

Risultato della ricerca: Articlepeer review

55 Citazioni (Scopus)


Poly(lactic acid)-based antimicrobial materials received considerable attention as promising systems to control microbial growth. The remarkable physicochemical properties of PLA such as renewability, biodegradability, and US Food and Drug Administration (FDA) approval for clinical use open up interesting perspectives for application in food packaging and biomedical materials. Nowadays, there is an increasing consumer demands for fresh, high-quality, and natural foods packaged with environmentally friendly materials that prolong the shelf life. The incorporation of antimicrobial agents into PLA-based polymers is likely to lead to the next generation of packaging materials. The development of antimicrobial PLA materials as a delivery system or coating for biomedical devices is also advantageous in order to reduce possible dose-dependent side effects and limit the phenomena of antibiotic resistance. This mini-review summarizes the most recent advances made in antimicrobial PLA-based polymers including their preparation, biocidal action, and applications. It also highlights the potential of PLA systems as efficient stabilizers-carriers of various kinds of antimicrobial additives including essential oils and other natural compounds, active particles and nanoparticles, and conventional and synthetic molecules.
Lingua originaleEnglish
pagine (da-a)7739-7756
Numero di pagine18
RivistaApplied Microbiology and Biotechnology
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

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