Antigen-specific T cells and cytokines detection as useful tool for understanding immunity against zoonotic infections.

Francesco Dieli, Guido Sireci, Marco Pio La Manna, Annalisa Agnone, Sara Villari, Fabrizio Vitale, Gesualdo Vesco, Santo Caracappa, Alessandra Torina

Risultato della ricerca: Articlepeer review

1 Citazioni (Scopus)

Abstract

Zoonoses include a broad range of diseases, that are becoming of great interest, due to the climate changing, that cause the adaptation of vectors to new niches and environments. Host immune responses play a crucial role in determining the outcome of infections, as documented by expansion of antigen-specific T cells during several zoonotic infections. Thus, understanding of the contribution of antigen-specific T-cell subsets in the host immune response is a powerful tool to evaluate the different immunological mechanisms involved in zoonotic infections and for the development of effective vaccines. In this paper we discuss the role of T cells in some eukaryotic and prokaryotic infectious models.
Lingua originaleEnglish
Numero di pagine8
RivistaCLINICAL & DEVELOPMENTAL IMMUNOLOGY
Volume2012
Stato di pubblicazionePublished - 2012

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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