Recently, the LRP10 gene has been associated with Parkinson’s disease (PD), Parkinson’s disease with dementia (PDD), anddementia with Lewy bodies (DLB). The aim of the present study was to evaluate the presence of mutations of the LRP10 gene inpatients with PD or DLB from Southern Italy. Sequencing analysis revealed only 2 missense and 3 synonymous variants inpatients and control subjects and a rare variant p.L622F in a PD case. These results suggest that LRP10 mutations are not afrequent cause of PD and DLB in Southern Italy.
|Numero di pagine||4|
|Stato di pubblicazione||Published - 2020|
All Science Journal Classification (ASJC) codes
- Clinical Neurology
- Psychiatry and Mental health