Ageing: From inflammation to cancer

Giulia Accardi, Roberto Monastero, Ferdinando Nicoletti, Giulia C. Leonardi, Massimo Libra

Risultato della ricerca: Articlepeer review

39 Citazioni (Scopus)

Abstract

Ageing is the major risk factor for cancer development. Hallmark of the ageing process is represented by inflammaging, which is a chronic and systemic low-grade inflammatory process. Inflammation is also a hallmark of cancer and is widely recognized to influence all cancer stages from cell transformation to metastasis. Therefore, inflammaging may represent the biological phenomena able to couple ageing process with cancer development. Here we review the molecular and cellular pathway involved in age-related chronic inflammation along with its potential triggers and their connection with cancer development.
Lingua originaleEnglish
pagine (da-a)1-7
Numero di pagine7
RivistaIMMUNITY & AGEING
Volume15
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • Immunology
  • Ageing

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