Ageing: From inflammation to cancer

Giulia Accardi, Roberto Monastero, Ferdinando Nicoletti, Giulia C. Leonardi, Massimo Libra

Risultato della ricerca: Article

23 Citazioni (Scopus)

Abstract

Ageing is the major risk factor for cancer development. Hallmark of the ageing process is represented by inflammaging, which is a chronic and systemic low-grade inflammatory process. Inflammation is also a hallmark of cancer and is widely recognized to influence all cancer stages from cell transformation to metastasis. Therefore, inflammaging may represent the biological phenomena able to couple ageing process with cancer development. Here we review the molecular and cellular pathway involved in age-related chronic inflammation along with its potential triggers and their connection with cancer development.
Lingua originaleEnglish
pagine (da-a)1-7
Numero di pagine7
RivistaIMMUNITY & AGEING
Volume15
Stato di pubblicazionePublished - 2018

Fingerprint

Inflammation
Neoplasms
Biological Phenomena
Neoplasm Metastasis

All Science Journal Classification (ASJC) codes

  • Immunology
  • Ageing

Cita questo

Accardi, G., Monastero, R., Nicoletti, F., Leonardi, G. C., & Libra, M. (2018). Ageing: From inflammation to cancer. IMMUNITY & AGEING, 15, 1-7.

Ageing: From inflammation to cancer. / Accardi, Giulia; Monastero, Roberto; Nicoletti, Ferdinando; Leonardi, Giulia C.; Libra, Massimo.

In: IMMUNITY & AGEING, Vol. 15, 2018, pag. 1-7.

Risultato della ricerca: Article

Accardi, G, Monastero, R, Nicoletti, F, Leonardi, GC & Libra, M 2018, 'Ageing: From inflammation to cancer', IMMUNITY & AGEING, vol. 15, pagg. 1-7.
Accardi G, Monastero R, Nicoletti F, Leonardi GC, Libra M. Ageing: From inflammation to cancer. IMMUNITY & AGEING. 2018;15:1-7.
Accardi, Giulia ; Monastero, Roberto ; Nicoletti, Ferdinando ; Leonardi, Giulia C. ; Libra, Massimo. / Ageing: From inflammation to cancer. In: IMMUNITY & AGEING. 2018 ; Vol. 15. pagg. 1-7.
@article{08895d21633e40d5a44147460dc206a2,
title = "Ageing: From inflammation to cancer",
abstract = "Ageing is the major risk factor for cancer development. Hallmark of the ageing process is represented by inflammaging, which is a chronic and systemic low-grade inflammatory process. Inflammation is also a hallmark of cancer and is widely recognized to influence all cancer stages from cell transformation to metastasis. Therefore, inflammaging may represent the biological phenomena able to couple ageing process with cancer development. Here we review the molecular and cellular pathway involved in age-related chronic inflammation along with its potential triggers and their connection with cancer development.",
keywords = "Ageing, Cancer, DAMPs, Inflammation, MiRna, Microbiota, Obesity, Senescence",
author = "Giulia Accardi and Roberto Monastero and Ferdinando Nicoletti and Leonardi, {Giulia C.} and Massimo Libra",
year = "2018",
language = "English",
volume = "15",
pages = "1--7",
journal = "IMMUNITY & AGEING",
issn = "1742-4933",

}

TY - JOUR

T1 - Ageing: From inflammation to cancer

AU - Accardi, Giulia

AU - Monastero, Roberto

AU - Nicoletti, Ferdinando

AU - Leonardi, Giulia C.

AU - Libra, Massimo

PY - 2018

Y1 - 2018

N2 - Ageing is the major risk factor for cancer development. Hallmark of the ageing process is represented by inflammaging, which is a chronic and systemic low-grade inflammatory process. Inflammation is also a hallmark of cancer and is widely recognized to influence all cancer stages from cell transformation to metastasis. Therefore, inflammaging may represent the biological phenomena able to couple ageing process with cancer development. Here we review the molecular and cellular pathway involved in age-related chronic inflammation along with its potential triggers and their connection with cancer development.

AB - Ageing is the major risk factor for cancer development. Hallmark of the ageing process is represented by inflammaging, which is a chronic and systemic low-grade inflammatory process. Inflammation is also a hallmark of cancer and is widely recognized to influence all cancer stages from cell transformation to metastasis. Therefore, inflammaging may represent the biological phenomena able to couple ageing process with cancer development. Here we review the molecular and cellular pathway involved in age-related chronic inflammation along with its potential triggers and their connection with cancer development.

KW - Ageing

KW - Cancer

KW - DAMPs

KW - Inflammation

KW - MiRna

KW - Microbiota

KW - Obesity

KW - Senescence

UR - http://hdl.handle.net/10447/281864

UR - http://www.immunityageing.com/

M3 - Article

VL - 15

SP - 1

EP - 7

JO - IMMUNITY & AGEING

JF - IMMUNITY & AGEING

SN - 1742-4933

ER -