Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.

Davide Vallese; Adriano Taddeo; Antonino Di Stefano; Davide Vallese; Lorena Delle Donne; Pantaleo Giannuzzi; Silvia Della Bella; Isabella Gnemmi; Silvia Della Bella; Alessandro Mezzani; Ermanno Eleuteri

Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.

Davide Vallese, Adriano Taddeo, Antonino Di Stefano, Davide Vallese, Lorena Delle Donne, Pantaleo Giannuzzi, Silvia Della Bella, Isabella Gnemmi, Silvia Della Bella, Alessandro Mezzani, Ermanno Eleuteri

Risultato della ricerca: Article › peer review

20 Citazioni (Scopus)

Abstract

The pathophysiology of chronic heart failure (CHF) involves multiple hystologic and molecular alterations. To determine the effects of physical training on circulating endothelial progenitor cells (EPCs), angiogenesis (angiogenin, angiopoietin-1 and -2, VEGF, Tie-2, SDF-1α) and inflammation (IL-6, CRP), we compared data obtained from 11 CHF pts before and after 3 months aerobic exercise training, to those from 10 non trained CHF pts (CHF-C group, age 64 + 2 years, NYHA 2). At the end of the study, EPCs count and AP-2 serum levels significantly increased in the CHF-TR group. These preliminary data suggest a significant effect of even a short program of physical training on angiogenic activation and endothelial dysfunction.

Lingua originale	English
pagine (da-a)	418-424
Numero di pagine	7
Rivista	Biomarkers
Volume	18
Stato di pubblicazione	Published - 2013

All Science Journal Classification (ASJC) codes

Biochemistry
Clinical Biochemistry
Health, Toxicology and Mutagenesis

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Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report. / Vallese, Davide; Taddeo, Adriano; Di Stefano, Antonino; Vallese, Davide; Delle Donne, Lorena; Giannuzzi, Pantaleo; Della Bella, Silvia; Gnemmi, Isabella; Della Bella, Silvia; Mezzani, Alessandro; Eleuteri, Ermanno.

In: Biomarkers, Vol. 18, 2013, pag. 418-424.

Risultato della ricerca: Article › peer review

Vallese, Davide ; Taddeo, Adriano ; Di Stefano, Antonino ; Vallese, Davide ; Delle Donne, Lorena ; Giannuzzi, Pantaleo ; Della Bella, Silvia ; Gnemmi, Isabella ; Della Bella, Silvia ; Mezzani, Alessandro ; Eleuteri, Ermanno. / Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report. In: Biomarkers. 2013 ; Vol. 18. pagg. 418-424.

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title = "Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.",

abstract = "The pathophysiology of chronic heart failure (CHF) involves multiple hystologic and molecular alterations. To determine the effects of physical training on circulating endothelial progenitor cells (EPCs), angiogenesis (angiogenin, angiopoietin-1 and -2, VEGF, Tie-2, SDF-1α) and inflammation (IL-6, CRP), we compared data obtained from 11 CHF pts before and after 3 months aerobic exercise training, to those from 10 non trained CHF pts (CHF-C group, age 64 + 2 years, NYHA 2). At the end of the study, EPCs count and AP-2 serum levels significantly increased in the CHF-TR group. These preliminary data suggest a significant effect of even a short program of physical training on angiogenic activation and endothelial dysfunction.",

author = "Davide Vallese and Adriano Taddeo and {Di Stefano}, Antonino and Davide Vallese and {Delle Donne}, Lorena and Pantaleo Giannuzzi and {Della Bella}, Silvia and Isabella Gnemmi and {Della Bella}, Silvia and Alessandro Mezzani and Ermanno Eleuteri",

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T1 - Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.

AU - Vallese, Davide

AU - Taddeo, Adriano

AU - Di Stefano, Antonino

AU - Vallese, Davide

AU - Delle Donne, Lorena

AU - Giannuzzi, Pantaleo

AU - Della Bella, Silvia

AU - Gnemmi, Isabella

AU - Della Bella, Silvia

AU - Mezzani, Alessandro

AU - Eleuteri, Ermanno

PY - 2013

Y1 - 2013

N2 - The pathophysiology of chronic heart failure (CHF) involves multiple hystologic and molecular alterations. To determine the effects of physical training on circulating endothelial progenitor cells (EPCs), angiogenesis (angiogenin, angiopoietin-1 and -2, VEGF, Tie-2, SDF-1α) and inflammation (IL-6, CRP), we compared data obtained from 11 CHF pts before and after 3 months aerobic exercise training, to those from 10 non trained CHF pts (CHF-C group, age 64 + 2 years, NYHA 2). At the end of the study, EPCs count and AP-2 serum levels significantly increased in the CHF-TR group. These preliminary data suggest a significant effect of even a short program of physical training on angiogenic activation and endothelial dysfunction.

AB - The pathophysiology of chronic heart failure (CHF) involves multiple hystologic and molecular alterations. To determine the effects of physical training on circulating endothelial progenitor cells (EPCs), angiogenesis (angiogenin, angiopoietin-1 and -2, VEGF, Tie-2, SDF-1α) and inflammation (IL-6, CRP), we compared data obtained from 11 CHF pts before and after 3 months aerobic exercise training, to those from 10 non trained CHF pts (CHF-C group, age 64 + 2 years, NYHA 2). At the end of the study, EPCs count and AP-2 serum levels significantly increased in the CHF-TR group. These preliminary data suggest a significant effect of even a short program of physical training on angiogenic activation and endothelial dysfunction.

UR - http://hdl.handle.net/10447/105555

M3 - Article

VL - 18

SP - 418

EP - 424

JO - Biomarkers

JF - Biomarkers

SN - 1354-750X

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