Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.

Davide Vallese, Adriano Taddeo, Antonino Di Stefano, Davide Vallese, Lorena Delle Donne, Pantaleo Giannuzzi, Isabella Gnemmi, Silvia Della Bella, Alessandro Mezzani, Ermanno Eleuteri

    Risultato della ricerca: Article

    18 Citazioni (Scopus)

    Abstract

    The pathophysiology of chronic heart failure (CHF) involves multiple hystologic and molecular alterations. To determine the effects of physical training on circulating endothelial progenitor cells (EPCs), angiogenesis (angiogenin, angiopoietin-1 and -2, VEGF, Tie-2, SDF-1α) and inflammation (IL-6, CRP), we compared data obtained from 11 CHF pts before and after 3 months aerobic exercise training, to those from 10 non trained CHF pts (CHF-C group, age 64 + 2 years, NYHA 2). At the end of the study, EPCs count and AP-2 serum levels significantly increased in the CHF-TR group. These preliminary data suggest a significant effect of even a short program of physical training on angiogenic activation and endothelial dysfunction.
    Lingua originaleEnglish
    pagine (da-a)418-424
    Numero di pagine7
    RivistaBiomarkers
    Volume18
    Stato di pubblicazionePublished - 2013

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Clinical Biochemistry
    • Health, Toxicology and Mutagenesis

    Fingerprint Entra nei temi di ricerca di 'Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report.'. Insieme formano una fingerprint unica.

  • Cita questo

    Vallese, D., Taddeo, A., Di Stefano, A., Vallese, D., Delle Donne, L., Giannuzzi, P., Gnemmi, I., Della Bella, S., Mezzani, A., & Eleuteri, E. (2013). Aerobic training and angiogenesis activation in patients with stable chronic heart failure: a preliminary report. Biomarkers, 18, 418-424.