ADVANCED ENDOSCOPIC IMAGING FOR SURVEILLANCE FOR DYSPLASIA AND COLORECTAL CANCER IN INFLAMMATORY BOWEL DISEASE: COULD THE PATHOLOGIST BE FURTHER HELPED?

Vincenzo Davide Palumbo, Giuseppe Damiano, Attilio Ignazio Lo Monte, Giovanni Tomasello, Mario Cottone, Salvatore Marasà, Dario Raimondo, Emanuele Sinagra, Marco Messina, Andreas Sturm, Francesca Rossi, Giovanni Tomasello, Tiziana Facella, Attilio I. Lo Monte, Marco Giunta, Gabriele Spinelli

Risultato della ricerca: Article

6 Citazioni (Scopus)

Abstract

Patients with inflammatory bowel disease (IBD) have an increased risk of developing intestinal cancer. The magnitude of that increased risk as well as how best to mitigate it remain a topic of ongoing investigation in the field. It is important to quantify the risk of colorectal cancer in association with IBD. The reported risk varies widely between studies. This is partly due to the different methodologies used in the studies. Because of the limitations of surveillance strategies based on the detection of dysplasia, advanced endoscopic imaging and techniques involving the detection of alterations in mucosal antigens and genetic abnormalities are being investigated. Development of new biomarkers, predicting future occurrence of colonic neoplasia may lead to more biomarker-based surveillance. There are promising results that may lead to more efficient surveillance in IBD patients and more general acceptance of its use. A multidisciplinary approach, involving in particular endoscopists and pathologists, together with a centralized patient management, could help to optimize treatments and follow-up measures, both of which could help to reduce the IBD-associated cancer risk.
Lingua originaleEnglish
pagine (da-a)26-38
Numero di pagine13
RivistaSaudi Journal of Gastroenterology
Volume20
Stato di pubblicazionePublished - 2014

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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  • Cita questo

    Palumbo, V. D., Damiano, G., Lo Monte, A. I., Tomasello, G., Cottone, M., Marasà, S., Raimondo, D., Sinagra, E., Messina, M., Sturm, A., Rossi, F., Tomasello, G., Facella, T., Lo Monte, A. I., Giunta, M., & Spinelli, G. (2014). ADVANCED ENDOSCOPIC IMAGING FOR SURVEILLANCE FOR DYSPLASIA AND COLORECTAL CANCER IN INFLAMMATORY BOWEL DISEASE: COULD THE PATHOLOGIST BE FURTHER HELPED? Saudi Journal of Gastroenterology, 20, 26-38.