Adipokines and lipoproteins: modulation by antihyperglycemic and hypolipidemic agents.

Manfredi Rizzo, Dragana Nikolic, Giuseppe Montalto, Hanaa S. Sallam, Nicola Abate, Ali A. Rizvi, Manfredi Rizzo

Risultato della ricerca: Articlepeer review

8 Citazioni (Scopus)


Adipose tissue is an endocrine organ that secretes a number of hormones and metabolically active substances that impact energy metabolism and insulin sensitivity. These inflammatory markers are collectively referred to as adipocytokines, or adipokines. Adipose tissue's functional capacity and metabolic activity vary among individuals, thus partly explaining the incomplete overlap between obesity and the metabolic syndrome. The functional failure of adipose tissues results in changed energy delivery and impaired glucose consumption, triggering self-regulatory mechanisms to maintain homeostasis. Antihyperglycemic, hypolipidemic, antiobesity, and angiotensin II receptor blocker drugs influence adipokine levels in different ways. However, clinical data are still scarce and the clinical relevance of these effects needs to be fully determined.
Lingua originaleEnglish
pagine (da-a)1-10
Numero di pagine9
RivistaMetabolic Syndrome and Related Disorders
Stato di pubblicazionePublished - 2014

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2700.2712???


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