ACUTE REVERSIBLE PARKINSONISM IN A DIABETIC-UREMIC PATIENT

Vincenzo La Bella, Chiara Cupidi, Federico Piccoli

Risultato della ricerca: Article

23 Citazioni (Scopus)

Abstract

Acute movement disorders with basal ganglia lesions have been recently described in diabetic-uremic patients of Asian descent. The process is often reversible, with a favourable clinical outcome. Metabolic (i.e. uremic toxins) and microangiopathic changes have been suggested to be involved in its pathophysiology, even though racial and/or genetic factors might play a role too. In this report, we present a Caucasian diabetic patient with a long-lasting mild uremia in which acute parkinsonism occurred after a steep and unexpected increase of the serum creatinine. The follow-up demonstrated a significant improvement of the neurological signs and symptoms, the creatinine level lowered close to the premorbid levels, and after several months the patient had fully recovered. Our case history suggests that this unusual clinical syndrome is most probably not restricted to Asian patients. Because its potentially favourable outcome, it should be regularly included in the differential diagnosis of acute movement disorders
Lingua originaleEnglish
pagine (da-a)601-603
RivistaClinical Neurology and Neurosurgery
Volume108
Stato di pubblicazionePublished - 2006

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Parkinsonian Disorders
Movement Disorders
Creatinine
Uremia
Basal Ganglia
Signs and Symptoms
Differential Diagnosis
Serum

All Science Journal Classification (ASJC) codes

  • Neurology
  • Surgery
  • Clinical Neurology

Cita questo

ACUTE REVERSIBLE PARKINSONISM IN A DIABETIC-UREMIC PATIENT. / La Bella, Vincenzo; Cupidi, Chiara; Piccoli, Federico.

In: Clinical Neurology and Neurosurgery, Vol. 108, 2006, pag. 601-603.

Risultato della ricerca: Article

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