Abstract
Hereditary aceruloplasminemia is a rare autosomal recessivedisease, firstly identified by Miyajima et al. in Japan in1987. The disease is caused by the absence of an a2-glycoprotein, the ceruloplasmin (Cp), a copper-containingferroxidase, mainly synthesized in hepatocytes and widelyexpressed, including the central nervous system, whichcatalyses the oxidation of ferrous to ferric iron, a changerequired for release of iron to plasma transferrin.
Lingua originale | English |
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pagine (da-a) | 395-399 |
Numero di pagine | 5 |
Rivista | Internal and Emergency Medicine |
Volume | 3 |
Stato di pubblicazione | Published - 2008 |
All Science Journal Classification (ASJC) codes
- ???subjectarea.asjc.2700.2724???
- ???subjectarea.asjc.2700.2711???