Hereditary aceruloplasminemia is a rare autosomal recessivedisease, firstly identified by Miyajima et al. in Japan in1987. The disease is caused by the absence of an a2-glycoprotein, the ceruloplasmin (Cp), a copper-containingferroxidase, mainly synthesized in hepatocytes and widelyexpressed, including the central nervous system, whichcatalyses the oxidation of ferrous to ferric iron, a changerequired for release of iron to plasma transferrin.
|Numero di pagine||5|
|Rivista||Internal and Emergency Medicine|
|Stato di pubblicazione||Published - 2008|
All Science Journal Classification (ASJC) codes
- Internal Medicine
- Emergency Medicine