Abdominal Wall Endometriosis: Myofibroblasts as a Possible Evidence of Metaplasia: A Case Report

Vito Chiantera, Matthias Haas, Eleonore Delarue, Matthias Haas, Mohamed Gamal Ibrahim, Elene Abesadze, Matthias Haas, Sylvia Mechsner, Vito Chiantera, Jalid Sehouli

Risultato della ricerca: Articlepeer review

6 Citazioni (Scopus)


In this study, we report about a patient with extra-uterine endometriosis (EM) in the abdominal wall muscle with evident metaplasia based on the abundant alpha smooth muscle actin (ASMA)-expressing myofibroblasts. Laparotomy excision of the abdominal wall EM was done following ultrasonographic evidence of a hypodense swelling in the right rectus abdominis, which was confirmed by MRI. Immunohistochemistry staining for ASMA and collagen I was done, with the results confirming that endometriotic stromal cells expressed both. Anterior abdominal wall endometriosis was suspected because of the patient's history of recurrent EM combined with the cyclic nature of symptoms. MRI is useful in determining the extent of the disease. In case of persisting symptoms even under hormonal treatment, surgical excision is mandatory. The expression of both ASMA and collagen I in and around EM lesions supports the notion of the metaplastic process in the course of disease development.
Lingua originaleEnglish
pagine (da-a)96-101
Numero di pagine6
RivistaGynecologic and Obstetric Investigation
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2700.2729???


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