A radical signal activates the epigenetic regulation of longevity

Mario Giuseppe Mirisola, Mario G. Mirisola, Valter D. Longo

Risultato della ricerca: Articlepeer review

10 Citazioni (Scopus)

Abstract

Hormesis is an adaptive stress response implicated in longevity regulation. Schroeder et al. (2013) have now connected stress, epigenetic changes, and aging in yeast by showing that mitochondria-derived reactive oxygen species modulate the chromatin binding capacity of the histone demethylase Rph1p at subtelomeres, resulting in lifespan extension.
Lingua originaleEnglish
pagine (da-a)812-813
Numero di pagine2
RivistaCell Metabolism
Volume17
Stato di pubblicazionePublished - 2013

All Science Journal Classification (ASJC) codes

  • Physiology
  • Molecular Biology
  • Cell Biology

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