A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era: selecting cases, matching clinical benefit: A position paper from the Italian Group of Haematopathology (G.I.E.)

Claudio Tripodo, Stefano Lazzi, Maria R. Ambrosio, Carbone, Stefano Aldo Pileri, Lucioni, Arianna Di Napoli, Tripodo, Zamò, Claudio Agostinelli, Remotti, Domenico Novero, Elena Sabattini, Stefano Ascani, Paulli, Luigi Ruco, Lorenzo Leoncini, Maurilio Ponzoni, Fabio Facchetti

Risultato della ricerca: Article

Abstract

An accurate diagnosis of clinically distinct subgroups of aggressive mature B cell lymphomas is crucial for the choice of proper treatment. Presently, precise recognition of these disorders relies on the combination of morphological, immunophenotypical, and cytogenetic/molecular features. The diagnostic workup in such situations implies the application of costly and time-consuming analyses, which are not always required, since an intensified treatment option is reasonably reserved to fit patients. The Italian Group of Haematopathology proposes herein a practical algorithm for the diagnosis of aggressive mature B cell lymphomas based on a stepwise approach, aimed to select cases deserving molecular analysis, in order to optimize time and resources still assuring the optimal management for any patient.
Lingua originaleEnglish
pagine (da-a)513-518
Numero di pagine6
RivistaVirchows Archiv
Volume475
Stato di pubblicazionePublished - 2019

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All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Cell Biology

Cita questo

Tripodo, C., Lazzi, S., Ambrosio, M. R., Carbone, Pileri, S. A., Lucioni, Di Napoli, A., Tripodo, Zamò, Agostinelli, C., Remotti, Novero, D., Sabattini, E., Ascani, S., Paulli, Ruco, L., Leoncini, L., Ponzoni, M., & Facchetti, F. (2019). A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era: selecting cases, matching clinical benefit: A position paper from the Italian Group of Haematopathology (G.I.E.). Virchows Archiv, 475, 513-518.