A Poly-L-Lactide scaffold with continuous gradient pore size for osteochondral regeneration validated in a microphysiological tissue system bioreactor

Risultato della ricerca: Other

Abstract

A microphysiological tissue system (MPS) bioreactor has been developed to replicate in vitro the in vivo OC physiological conditions. The MPS allows separate control of the chondral and osseous environment while permitting communication between chondrocytes and osteoblasts across the OC junction, similar to the conditions of OC tissue in vivo. We have used here our MPS system to validate the TIPS -generated pore-gradient PLLA scaffold.
Lingua originaleEnglish
Numero di pagine1
Stato di pubblicazionePublished - 2016

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Bioreactors
Regeneration
Chondrocytes
Osteoblasts
Cartilage
poly(lactide)

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title = "A Poly-L-Lactide scaffold with continuous gradient pore size for osteochondral regeneration validated in a microphysiological tissue system bioreactor",
abstract = "A microphysiological tissue system (MPS) bioreactor has been developed to replicate in vitro the in vivo OC physiological conditions. The MPS allows separate control of the chondral and osseous environment while permitting communication between chondrocytes and osteoblasts across the OC junction, similar to the conditions of OC tissue in vivo. We have used here our MPS system to validate the TIPS -generated pore-gradient PLLA scaffold.",
author = "Brucato, {Valerio Maria Bartolo} and {La Carrubba}, Vincenzo and Gioacchino Conoscenti",
year = "2016",
language = "English",

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TY - CONF

T1 - A Poly-L-Lactide scaffold with continuous gradient pore size for osteochondral regeneration validated in a microphysiological tissue system bioreactor

AU - Brucato, Valerio Maria Bartolo

AU - La Carrubba, Vincenzo

AU - Conoscenti, Gioacchino

PY - 2016

Y1 - 2016

N2 - A microphysiological tissue system (MPS) bioreactor has been developed to replicate in vitro the in vivo OC physiological conditions. The MPS allows separate control of the chondral and osseous environment while permitting communication between chondrocytes and osteoblasts across the OC junction, similar to the conditions of OC tissue in vivo. We have used here our MPS system to validate the TIPS -generated pore-gradient PLLA scaffold.

AB - A microphysiological tissue system (MPS) bioreactor has been developed to replicate in vitro the in vivo OC physiological conditions. The MPS allows separate control of the chondral and osseous environment while permitting communication between chondrocytes and osteoblasts across the OC junction, similar to the conditions of OC tissue in vivo. We have used here our MPS system to validate the TIPS -generated pore-gradient PLLA scaffold.

UR - http://hdl.handle.net/10447/209631

M3 - Other

ER -