A multivariate insight into ionic liquids toxicities

Renato Noto, Francesca D'Anna, Salvatore Scirè, Alessio Paternò, Giuseppe Musumarra

Risultato della ricerca: Article

18 Citazioni (Scopus)

Abstract

A multivariate insight into Ionic Liquids' (ILs) toxicity, a broad term highly dependent on the biological systems adopted as "sensors", addressed four main groups of toxicities: aquatic toxicity, toxicity towards fungi and bacteria, cytotoxicity towards IPC-81 rat cell lines and acetylcholinesterase enzyme inhibition. This approach, summarizing toxicity information available from a huge amount of scattered literature data, allowed derivation of aquatic toxicity scores for 104 ILs and bacteria and fungi toxicity scores for 87 ILs as well as identification of a correlation between aquatic ecotoxicity and the response of IPC-81 rat cell lines. Further evidence on the effects of cation structural features such as the increase of IL toxicity on increasing the length of the side chain and its decrease when oxygen atoms are present in the side chain was obtained. Maximum dialkyloxyether imidazolium toxicity was observed for ILs having 7-9 carbon atoms in each side chain, while toxicity decreased for ILs with a higher number of carbons, probably due to the formation of micellar aggregates.
Lingua originaleEnglish
pagine (da-a)23985-24000
Numero di pagine16
RivistaRSC Advances
Volume4
Stato di pubblicazionePublished - 2014

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Ionic Liquids
Ionic liquids
Toxicity
Fungi
Rats
Bacteria
Carbon
Cells
Enzyme inhibition
Atoms
Biological systems
Acetylcholinesterase
Cytotoxicity
Cations
Positive ions
Oxygen

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Cita questo

Noto, R., D'Anna, F., Scirè, S., Paternò, A., & Musumarra, G. (2014). A multivariate insight into ionic liquids toxicities. RSC Advances, 4, 23985-24000.

A multivariate insight into ionic liquids toxicities. / Noto, Renato; D'Anna, Francesca; Scirè, Salvatore; Paternò, Alessio; Musumarra, Giuseppe.

In: RSC Advances, Vol. 4, 2014, pag. 23985-24000.

Risultato della ricerca: Article

Noto, R, D'Anna, F, Scirè, S, Paternò, A & Musumarra, G 2014, 'A multivariate insight into ionic liquids toxicities', RSC Advances, vol. 4, pagg. 23985-24000.
Noto R, D'Anna F, Scirè S, Paternò A, Musumarra G. A multivariate insight into ionic liquids toxicities. RSC Advances. 2014;4:23985-24000.
Noto, Renato ; D'Anna, Francesca ; Scirè, Salvatore ; Paternò, Alessio ; Musumarra, Giuseppe. / A multivariate insight into ionic liquids toxicities. In: RSC Advances. 2014 ; Vol. 4. pagg. 23985-24000.
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