TY - JOUR
T1 - A feline rotavirus G3P[9] carries traces of multiple reassortment events and resembles rare human G3P[9] rotaviruses
AU - Giammanco, Giovanni
AU - De Grazia, Simona
AU - Matthijnssens, Jelle
AU - Lavazza, null
AU - Ciarlet, null
AU - Decaro, null
AU - Martella, Vito
AU - Buonavoglia, null
AU - Lorusso, null
AU - Potgieter, null
AU - Bányai, Kristián
PY - 2011
Y1 - 2011
N2 - The full-length genome sequence of a feline G3P[9] rotavirus (RV) strain, BA222, identified from the intestinal content of an adult cat, was determined. Strain BA222 possessed a G3-P[9]-I2-R2-C2-M2-A3-N1-T3-E2-H3 genomic constellation, differing substantially from other feline RVs. Phylogenetic analyses of each genome segment revealed common origins with selected animal and zoonotic human RVs, notably with rare multi-reassortant human G3P[9] RVs (Ita/PAI58/96 and Ita/PAH136/96). Altogether, the findings suggest that feline RVs are genetically diverse and that human RVs may occasionally originate either directly or indirectly (via reassortment) from feline RVs.
AB - The full-length genome sequence of a feline G3P[9] rotavirus (RV) strain, BA222, identified from the intestinal content of an adult cat, was determined. Strain BA222 possessed a G3-P[9]-I2-R2-C2-M2-A3-N1-T3-E2-H3 genomic constellation, differing substantially from other feline RVs. Phylogenetic analyses of each genome segment revealed common origins with selected animal and zoonotic human RVs, notably with rare multi-reassortant human G3P[9] RVs (Ita/PAI58/96 and Ita/PAH136/96). Altogether, the findings suggest that feline RVs are genetically diverse and that human RVs may occasionally originate either directly or indirectly (via reassortment) from feline RVs.
UR - http://hdl.handle.net/10447/55931
UR - http://www.ncbi.nlm.nih.gov/pubmed/21228122
M3 - Article
SN - 0022-1317
VL - 92
SP - 1214
EP - 1221
JO - Journal of General Virology
JF - Journal of General Virology
ER -