2-Cinnamamido, 2-(3-phenylpropiolamido), and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity, and mechanism of action

Maria Grazia Cusimano, Giandomenico Amico, Maria Valeria Raimondi, Giuseppe Daidone, Benedetta Maggio, Demetrio Raffa, Ernest Hamel, Pier Giulio Conaldi, Giandomenico Amico, Anna Carollo, Demetrio Raffa, Giuseppe Daidone, Maria Valeria Raimondi, Benedetta Maggio, Ruoli Bai, Maria Grazia Cusimano

Risultato della ricerca: Articlepeer review

5 Citazioni (Scopus)

Abstract

Several new benzamides 4a-q were synthesized by stirring in pyridine the acid chlorides 3a-q with the appropriate anthranilamide derivatives 2a-g. Some of the synthesized compounds were evaluated for their in vitro antiproliferative activity against a panel of 5 human cell lines (K562 human chronic myelogenous leukemia cells, MCF-7 breast cancer cells, HTC-116 and HT26 colon cancer cells and NCI H460 non-small cell lung cancer cells).
Lingua originaleEnglish
pagine (da-a)427-435
Numero di pagine9
RivistaEuropean Journal of Medicinal Chemistry
Volume65
Stato di pubblicazionePublished - 2013

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.1600.1605???

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