This review covering literature reports from the beginning of this century to 2016 describes the synthetic pathways, the antitumor activity, the structure-activity relationship and, whenever reported, the possible mechanism of action of 1,3,5-triazine derivatives as well as of their hetero-fused compounds. Many 1,3,5-triazine derivatives, both uncondensed and hetero-fused, have shown remarkable antitumor activities and some of them reached clinical development.
|Numero di pagine||27|
|Rivista||European Journal of Medicinal Chemistry|
|Stato di pubblicazione||Published - 2017|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry