Uncommon clinical presentation of Kimura's disease as bilateral retroauricular masses in a young Malian male: Successful surgical approach

Antonio Cascio, Georgi Tchernev, Ieni, Alessandro Sindoni, Uwe Wollina, Roccia, Maximov, Fioranelli, Anastasiya Atanasova Chokoeva, Patterson, Lotti, Claudio Guarneri, Maria Gioffre-Florio, Fausto Fama, Cascio, Torello Lotti, Patterson, Patterson

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We present a case of a 27 year-old Malian male referred to our hospital for two large, painless retroauricolar masses that had appeared two years earlier. Bilateral cervical painless lymphadenopathy was present at physical examination, without any other systemic symptoms. His history was relevant for bilateral Kimura's disease lesions resected 5 years earlier in the same locations. Lymphocytosis and a mild hypereosinophilia were found in routine blood tests, together with increased total IgE levels. After surgery, histology showed lymphoid infiltrates with reactive prominent germinal centres containing eosinophils, suggesting relapse of Kimura's disease, in the context of nonencapsulated fibrous proliferation with discontinuous collagen fibers, consistent with keloid. Three months after removal of retroauricular masses, abnormal laboratory findings reverted to normal. To the best our knowledge, this is the first case in literature of bilateral keloid lesions developed after surgery for Kimura Disease and harbouring its histopathologic features. Clinicians should be aware of these unusual reactive phenomena and their possible simulators.
Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalJOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS
Volume30
Publication statusPublished - 2016

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy
  • Physiology
  • Immunology
  • Oncology
  • Endocrinology
  • Physiology (medical)
  • Cancer Research

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