The present study investigated primary human hepatocyte cultures obtained from liver specimens of patients affected by cirrhosis and HCC, their proliferation and transformation. The degree of invasiveness of cells acquiring neoplastic characteristics was studied with a transwell migration assay. With the present study, we are the first to have identified and describe the existence of humanhepatocytes near the cancerous lesion that can transform in HCC in vitro.
|Number of pages||13|
|Journal||International Journal of Oncology|
|Publication status||Published - 2015|
All Science Journal Classification (ASJC) codes
- Cancer Research