Transcranial Magnetic Resonance-guided Focused Ultrasound Surgery (tcMRgFUS) at 1.5T: this is how we do it

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Abstract

Purpose: Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is an emerging minimally invasive treatment for many neurological conditions. We present the imaging protocol and the technological methods used in the first 1.5T magnetic resonance scanner.Background: Current experiences of tcMRgFUS applications using 3T MRI units include for the treatment of movement disorders such as essential tremor, tremor dominant unilateral idiopathic Parkinson disease as well as for the treatment of neuropathic pain. This technology is constantly expanding the range of clinical indication and application even in 1.5T MR scanner. Findings and procedure details: In our experiences the Focused Ultrasound equipment was integrated with an MRI unit operating at 1.5T. It consists of a hemispheric 1024-element phased-array transducer operating at 650 kHz as those used with 3.0T MRI units. A dedicated 2 channel flexible head coil was developed to maintain an adequate signal to noise ratio (SNR). This coil consists of two silicon-coated rings that are embedded into the elastic membrane used with 3T systems. In our preliminary experience we preferred to use T2-weighted (T2-w) and/or inversion recovery for white matter T2-w sequences for planning and monitoring the procedures. With the two Head coil, thermal imaging resulted reliable and T2-w sequences provided the expected SNR for planning and monitoring the procedure resulting in precise treatment planning and a good localization of the lesion during the ongoing treatment.Conclusion: TcMRgFUS is taking place as a revolutionary treating modality for several neurological disorders. The results obtained with a 1.5T unit lead us to imagine a greater spread of this promising, emerging technology.
Original languageEnglish
Number of pages1
Publication statusPublished - 2018

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Magnetic Resonance Spectroscopy
Signal-To-Noise Ratio
Head
Technology
Essential Tremor
Therapeutics
Movement Disorders
Neuralgia
Tremor
Silicon
Nervous System Diseases
Transducers
Parkinson Disease
Hot Temperature
Equipment and Supplies
Membranes

Cite this

@conference{41a7689fcfdb417ca3694718573184ba,
title = "Transcranial Magnetic Resonance-guided Focused Ultrasound Surgery (tcMRgFUS) at 1.5T: this is how we do it",
abstract = "Purpose: Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is an emerging minimally invasive treatment for many neurological conditions. We present the imaging protocol and the technological methods used in the first 1.5T magnetic resonance scanner.Background: Current experiences of tcMRgFUS applications using 3T MRI units include for the treatment of movement disorders such as essential tremor, tremor dominant unilateral idiopathic Parkinson disease as well as for the treatment of neuropathic pain. This technology is constantly expanding the range of clinical indication and application even in 1.5T MR scanner. Findings and procedure details: In our experiences the Focused Ultrasound equipment was integrated with an MRI unit operating at 1.5T. It consists of a hemispheric 1024-element phased-array transducer operating at 650 kHz as those used with 3.0T MRI units. A dedicated 2 channel flexible head coil was developed to maintain an adequate signal to noise ratio (SNR). This coil consists of two silicon-coated rings that are embedded into the elastic membrane used with 3T systems. In our preliminary experience we preferred to use T2-weighted (T2-w) and/or inversion recovery for white matter T2-w sequences for planning and monitoring the procedures. With the two Head coil, thermal imaging resulted reliable and T2-w sequences provided the expected SNR for planning and monitoring the procedure resulting in precise treatment planning and a good localization of the lesion during the ongoing treatment.Conclusion: TcMRgFUS is taking place as a revolutionary treating modality for several neurological disorders. The results obtained with a 1.5T unit lead us to imagine a greater spread of this promising, emerging technology.",
author = "Massimo Midiri and Cesare Gagliardo and Giorgio Collura and Roberto Lagalla and Bartolotta, {Tommaso Vincenzo} and Maurizio Marrale and Laura Geraci",
year = "2018",
language = "English",

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T1 - Transcranial Magnetic Resonance-guided Focused Ultrasound Surgery (tcMRgFUS) at 1.5T: this is how we do it

AU - Midiri, Massimo

AU - Gagliardo, Cesare

AU - Collura, Giorgio

AU - Lagalla, Roberto

AU - Bartolotta, Tommaso Vincenzo

AU - Marrale, Maurizio

AU - Geraci, Laura

PY - 2018

Y1 - 2018

N2 - Purpose: Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is an emerging minimally invasive treatment for many neurological conditions. We present the imaging protocol and the technological methods used in the first 1.5T magnetic resonance scanner.Background: Current experiences of tcMRgFUS applications using 3T MRI units include for the treatment of movement disorders such as essential tremor, tremor dominant unilateral idiopathic Parkinson disease as well as for the treatment of neuropathic pain. This technology is constantly expanding the range of clinical indication and application even in 1.5T MR scanner. Findings and procedure details: In our experiences the Focused Ultrasound equipment was integrated with an MRI unit operating at 1.5T. It consists of a hemispheric 1024-element phased-array transducer operating at 650 kHz as those used with 3.0T MRI units. A dedicated 2 channel flexible head coil was developed to maintain an adequate signal to noise ratio (SNR). This coil consists of two silicon-coated rings that are embedded into the elastic membrane used with 3T systems. In our preliminary experience we preferred to use T2-weighted (T2-w) and/or inversion recovery for white matter T2-w sequences for planning and monitoring the procedures. With the two Head coil, thermal imaging resulted reliable and T2-w sequences provided the expected SNR for planning and monitoring the procedure resulting in precise treatment planning and a good localization of the lesion during the ongoing treatment.Conclusion: TcMRgFUS is taking place as a revolutionary treating modality for several neurological disorders. The results obtained with a 1.5T unit lead us to imagine a greater spread of this promising, emerging technology.

AB - Purpose: Magnetic Resonance-guided Focused Ultrasound (MRgFUS) is an emerging minimally invasive treatment for many neurological conditions. We present the imaging protocol and the technological methods used in the first 1.5T magnetic resonance scanner.Background: Current experiences of tcMRgFUS applications using 3T MRI units include for the treatment of movement disorders such as essential tremor, tremor dominant unilateral idiopathic Parkinson disease as well as for the treatment of neuropathic pain. This technology is constantly expanding the range of clinical indication and application even in 1.5T MR scanner. Findings and procedure details: In our experiences the Focused Ultrasound equipment was integrated with an MRI unit operating at 1.5T. It consists of a hemispheric 1024-element phased-array transducer operating at 650 kHz as those used with 3.0T MRI units. A dedicated 2 channel flexible head coil was developed to maintain an adequate signal to noise ratio (SNR). This coil consists of two silicon-coated rings that are embedded into the elastic membrane used with 3T systems. In our preliminary experience we preferred to use T2-weighted (T2-w) and/or inversion recovery for white matter T2-w sequences for planning and monitoring the procedures. With the two Head coil, thermal imaging resulted reliable and T2-w sequences provided the expected SNR for planning and monitoring the procedure resulting in precise treatment planning and a good localization of the lesion during the ongoing treatment.Conclusion: TcMRgFUS is taking place as a revolutionary treating modality for several neurological disorders. The results obtained with a 1.5T unit lead us to imagine a greater spread of this promising, emerging technology.

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