The vaccinaTion & Hpv Knowledge (THinK) questionnaire: a reliability and validity study on a sample of women living in Sicily (southern-Italy)

Gregorio Serra, Domenica Matranga, Gregorio Serra, Rossella Guarneri, Marcello Noto, Alessia Pivetti, Vincenza Maria Arculeo, Maria Francesca Guarneri, Gregorio Serra, Antonio Spera, Cristina Lumia, Marcello Noto, Rossella Guarneri, Antonio Spera, Antonio Spera, Alessia Pivetti, Antonio Spera, Marcello Noto, Maria Francesca Guarneri, Rossella Guarneri

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2 Citations (Scopus)


Objective. The aim of this study was to introduce the VaccinaTion & Hpv Knowledge (THinK) questionnaire to assess knowledge about human papillomavirus (HPV) and attitude to HPV-vaccination. Its reliability and validity was demonstrated in a sample of women living in Sicily (southern Italy).Methods. A cross-sectional survey was conducted on a sample of 220 women at the "Paolo Giaccone" University Hospital in Palermo (Sicily), aged 18-61. Data were analyzed through Cronbach's alpha and exploratory factor analysis, followed by a structural equation model with measurement component. The two-level data structure was explicitly considered.Results. Three dimensions were found: "knowledge of HPV infection (kHPV), "Attitude to be vaccinated against HPV (aHPV)" and "Knowledge about vaccines (KV)" (97% overall explained variance). Internal consistency was good for the whole questionnaire (0.82) and the first dimension (0.88) and acceptable for the second (0.78) and the third dimension (0.73). 23% of women showed no or little knowledge of HPV and 44.3% of women had no or little knowledge about HPV induced lesions.Discussion. The use of a validated questionnaire may serve as a useful measure to assess general knowledge about HPV and attitude towards vaccination against HPV in the primary prevention setting.
Original languageEnglish
Pages (from-to)e6254-
Number of pages13
Publication statusPublished - 2019

All Science Journal Classification (ASJC) codes

  • General Neuroscience
  • General Biochemistry,Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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