The role of inflammation in lymphoma

Claudio Tripodo, Ilaria Torselli, Alessia Burocchi, Caterina Vitali, Sara Sandri, Laura Botti, Andrea Tomirotti, Chiara Ratti, Sabina Sangaletti, Claudia Chiodoni, Mario P. Colombo

Research output: Chapter in Book/Report/Conference proceedingChapter

63 Citations (Scopus)

Abstract

Human lymphomas usually develop in specialized tissue microenvironments characterized by different populations of accessory stromal and lymphoid cells that interact with malignant cells. A clinical role of the tumor microenvironment has recently emerged, bringing new knowledge and suggesting new ideas and targets for treatment. This chapter analyzes the microenvironment in human lymphomas highlighting the role of inflammation in their pathogenesis. Microenvironmental specificity is detailed according to different models including classic Hodgkin lymphoma (HL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), peripheral T-cell lymphoma, unspecified and angioimmunoblastic T-cell lymphoma (AITL).
Original languageEnglish
Title of host publicationADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
Pages315-333
Number of pages19
Publication statusPublished - 2014

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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