The Fate of Nephrons in Congenital Obstructive Nephropathy: Adult Recovery is Limited by Nephron Number Despite Early Release of Obstruction

Maria Sergio, Carolina I. Galarreta, Michael S. Forbes, Michael S. Forbes, Maria Sergio, Barbara A. Thornhill, Robert L. Chevalier, Michael S. Forbes

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Urinary tract obstruction and reduced nephron number often occur together as a result of maldevelopment of kidneys and urinary tract. We wished to determine the role of nephron number on the adaptation of remaining nephrons of mice subjected to neonatal partial unilateral ureteral obstruction (UUO) and followed through adulthood.
Original languageEnglish
Pages (from-to)1463-1472
Number of pages10
JournalTHE JOURNAL OF UROLOGY
Volume194
Publication statusPublished - 2015

All Science Journal Classification (ASJC) codes

  • Urology

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