Temporal control of xyloglucan self-assembly into layered structures by radiation-induced degradation

Simona Todaro, Maria Antonietta Sabatino, Clelia Dispenza, Pasquale Picone, Maria Laura Di Giacinto, Maria Rosalia Mangione, Donatella Bulone

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Partially degalactosylated xyloglucan from tamarind seeds (Deg-XG) is a very appealing biopolymer for the production of in situ gelling systems at physiological temperature. In this work, we observe that the morphology of hydrogels evolves towards high degrees of structural organization with time, yielding to dense stacks of thin membranes within 24 h of incubation at 37 °C. We also explore the possibility offered by gamma irradiation of controlling the time scale of this phenomenon, the final morphology and mechanical properties of the system. Structural and molecular modifications of Deg-XG with dose are investigated by FTIR, dynamic light scattering (DLS) and rotational viscosimetry. The impact on gelation ability and gel strength is studied by rheological analysis. The morphology evolution is investigated by SEM analysis, and absence of cytotoxicity verified by MTS assay and optical microscopy of neuroblastoma cells.
Original languageEnglish
Pages (from-to)382-390
Number of pages9
JournalCarbohydrate Polymers
Volume152
Publication statusPublished - 2016

All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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