Temperature-induced self-assembly of degalactosylated xyloglucan at low concentration

Clelia Dispenza, Maria Antonietta Sabatino, Simona Todaro, Maria Grazia Ortore, Pier Luigi San Biagio, Rosa Passantino, Donatella Bulone

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4 Citations (Scopus)

Abstract

Xyloglucan is a natural polysaccharide having a cellulose-like backbone and hydroxyl groups-rich side-chains. In its native form the polymer is water-soluble and forms gel only in presence of selected co-solutes. When a given fraction of galactosyl residues are removed by enzymatic reaction, the polymer acquires the ability to form a gel in aqueous solution at physiological temperatures, a property of great interest for biomedical/pharmaceutical applications. This work presents data on the effect of a temperature increase on degalactosylated xyloglucan dispersed in water at concentration low enough not to run into macroscopic gelation. Results obtained over a wide interval of length scales show that, on increasing temperature, individual polymer chains and pre-existing clusters self-assemble into larger structures. The process implies a structural rearrangement over a few nanometers scale and an increase of dynamics homogeneity. The relation of these findings to coil-globule transition and phase separation is discussed.
Original languageEnglish
Pages (from-to)1727-1735
Number of pages9
JournalJOURNAL OF POLYMER SCIENCE. PART B, POLYMER PHYSICS
Volume53
Publication statusPublished - 2015

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All Science Journal Classification (ASJC) codes

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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