T2-mapping of the sacroiliac joints at 1.5 Tesla: a feasibility and reproducibility study

Roberto Lagalla, Domenico Albano, Massimo Galia, Francesco Ciccia, Massimo Midiri, Luca Maria Sconfienza, Renato Cuocolo, Vito Chianca, Arturo Brunetti, Rodolfo Bignone

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective: To evaluate the reproducibility of T2 relaxation time measurements of the sacroiliac joints at 1.5 T. Materials and methods: Healthy volunteers underwent an oblique axial multislice multiecho spin-echo sequence of the sacroiliac joints at 1.5 T. Regions of interest were manually drawn using a dedicated software by two musculoskeletal radiologists to include the cartilaginous part of the sacroiliac joints. A senior radiologist performed the measurement twice, while a resident measured once. Intra- and inter-observer reproducibility was tested using the Bland-Altman method. Association between sex and T2 relaxation times was tested using the Mann-Whitney U test. Correlation between T2 relaxation times and body mass index (BMI) was tested using the Spearman’s rho. Results: Eighty sacroiliac joints of 40 subjects (mean age: 28 ± 4.8 years, range: 20–43; mean BMI: 23.3 ± 3.1, range: 18.9–30) were imaged. The mean T2 values obtained by the senior radiologist in the first series of measurements were 42 ± 4.4 ms, whereas in the second series were 40.7 ± 4.5 ms. The mean T2 values obtained by the radiology resident were 41.1 ± 4.2 ms. Intra-observer reproducibility was 88% (coefficient of repeatability = 3.8; bias = 1.28; p <.001), while inter-observer reproducibility was 86% (4.7; −.88; p <.001). There was significant association between sex and T2 relaxation times (p =.024) and significant inverse correlation between T2 relaxation times and BMI (r = −.340, p =.002). Conclusion: The assessment of T2 relaxation time measurements of sacroiliac joints seems to be highly reproducible at 1.5 T. Further studies could investigate the potential clinical application of this tool in the sacroiliac joints.
Original languageEnglish
Pages (from-to)1691-1696
Number of pages6
JournalSkeletal Radiology
Volume47
Publication statusPublished - 2018

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Sacroiliac Joint
Feasibility Studies
Body Mass Index
Nonparametric Statistics
Radiology
Healthy Volunteers
Software
Radiologists

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

T2-mapping of the sacroiliac joints at 1.5 Tesla: a feasibility and reproducibility study. / Lagalla, Roberto; Albano, Domenico; Galia, Massimo; Ciccia, Francesco; Midiri, Massimo; Sconfienza, Luca Maria; Cuocolo, Renato; Chianca, Vito; Brunetti, Arturo; Bignone, Rodolfo.

In: Skeletal Radiology, Vol. 47, 2018, p. 1691-1696.

Research output: Contribution to journalArticle

Lagalla, Roberto ; Albano, Domenico ; Galia, Massimo ; Ciccia, Francesco ; Midiri, Massimo ; Sconfienza, Luca Maria ; Cuocolo, Renato ; Chianca, Vito ; Brunetti, Arturo ; Bignone, Rodolfo. / T2-mapping of the sacroiliac joints at 1.5 Tesla: a feasibility and reproducibility study. In: Skeletal Radiology. 2018 ; Vol. 47. pp. 1691-1696.
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abstract = "Objective: To evaluate the reproducibility of T2 relaxation time measurements of the sacroiliac joints at 1.5 T. Materials and methods: Healthy volunteers underwent an oblique axial multislice multiecho spin-echo sequence of the sacroiliac joints at 1.5 T. Regions of interest were manually drawn using a dedicated software by two musculoskeletal radiologists to include the cartilaginous part of the sacroiliac joints. A senior radiologist performed the measurement twice, while a resident measured once. Intra- and inter-observer reproducibility was tested using the Bland-Altman method. Association between sex and T2 relaxation times was tested using the Mann-Whitney U test. Correlation between T2 relaxation times and body mass index (BMI) was tested using the Spearman’s rho. Results: Eighty sacroiliac joints of 40 subjects (mean age: 28 ± 4.8 years, range: 20–43; mean BMI: 23.3 ± 3.1, range: 18.9–30) were imaged. The mean T2 values obtained by the senior radiologist in the first series of measurements were 42 ± 4.4 ms, whereas in the second series were 40.7 ± 4.5 ms. The mean T2 values obtained by the radiology resident were 41.1 ± 4.2 ms. Intra-observer reproducibility was 88{\%} (coefficient of repeatability = 3.8; bias = 1.28; p <.001), while inter-observer reproducibility was 86{\%} (4.7; −.88; p <.001). There was significant association between sex and T2 relaxation times (p =.024) and significant inverse correlation between T2 relaxation times and BMI (r = −.340, p =.002). Conclusion: The assessment of T2 relaxation time measurements of sacroiliac joints seems to be highly reproducible at 1.5 T. Further studies could investigate the potential clinical application of this tool in the sacroiliac joints.",
keywords = "Cartilage; Magnetic resonance imaging; Sacroiliac joint; T2 mapping; Adult; Feasibility Studies; Female; Healthy Volunteers; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Reproducibility of Results; Sacroiliac Joint; Radiology, Nuclear Medicine and Imaging",
author = "Roberto Lagalla and Domenico Albano and Massimo Galia and Francesco Ciccia and Massimo Midiri and Sconfienza, {Luca Maria} and Renato Cuocolo and Vito Chianca and Arturo Brunetti and Rodolfo Bignone",
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TY - JOUR

T1 - T2-mapping of the sacroiliac joints at 1.5 Tesla: a feasibility and reproducibility study

AU - Lagalla, Roberto

AU - Albano, Domenico

AU - Galia, Massimo

AU - Ciccia, Francesco

AU - Midiri, Massimo

AU - Sconfienza, Luca Maria

AU - Cuocolo, Renato

AU - Chianca, Vito

AU - Brunetti, Arturo

AU - Bignone, Rodolfo

PY - 2018

Y1 - 2018

N2 - Objective: To evaluate the reproducibility of T2 relaxation time measurements of the sacroiliac joints at 1.5 T. Materials and methods: Healthy volunteers underwent an oblique axial multislice multiecho spin-echo sequence of the sacroiliac joints at 1.5 T. Regions of interest were manually drawn using a dedicated software by two musculoskeletal radiologists to include the cartilaginous part of the sacroiliac joints. A senior radiologist performed the measurement twice, while a resident measured once. Intra- and inter-observer reproducibility was tested using the Bland-Altman method. Association between sex and T2 relaxation times was tested using the Mann-Whitney U test. Correlation between T2 relaxation times and body mass index (BMI) was tested using the Spearman’s rho. Results: Eighty sacroiliac joints of 40 subjects (mean age: 28 ± 4.8 years, range: 20–43; mean BMI: 23.3 ± 3.1, range: 18.9–30) were imaged. The mean T2 values obtained by the senior radiologist in the first series of measurements were 42 ± 4.4 ms, whereas in the second series were 40.7 ± 4.5 ms. The mean T2 values obtained by the radiology resident were 41.1 ± 4.2 ms. Intra-observer reproducibility was 88% (coefficient of repeatability = 3.8; bias = 1.28; p <.001), while inter-observer reproducibility was 86% (4.7; −.88; p <.001). There was significant association between sex and T2 relaxation times (p =.024) and significant inverse correlation between T2 relaxation times and BMI (r = −.340, p =.002). Conclusion: The assessment of T2 relaxation time measurements of sacroiliac joints seems to be highly reproducible at 1.5 T. Further studies could investigate the potential clinical application of this tool in the sacroiliac joints.

AB - Objective: To evaluate the reproducibility of T2 relaxation time measurements of the sacroiliac joints at 1.5 T. Materials and methods: Healthy volunteers underwent an oblique axial multislice multiecho spin-echo sequence of the sacroiliac joints at 1.5 T. Regions of interest were manually drawn using a dedicated software by two musculoskeletal radiologists to include the cartilaginous part of the sacroiliac joints. A senior radiologist performed the measurement twice, while a resident measured once. Intra- and inter-observer reproducibility was tested using the Bland-Altman method. Association between sex and T2 relaxation times was tested using the Mann-Whitney U test. Correlation between T2 relaxation times and body mass index (BMI) was tested using the Spearman’s rho. Results: Eighty sacroiliac joints of 40 subjects (mean age: 28 ± 4.8 years, range: 20–43; mean BMI: 23.3 ± 3.1, range: 18.9–30) were imaged. The mean T2 values obtained by the senior radiologist in the first series of measurements were 42 ± 4.4 ms, whereas in the second series were 40.7 ± 4.5 ms. The mean T2 values obtained by the radiology resident were 41.1 ± 4.2 ms. Intra-observer reproducibility was 88% (coefficient of repeatability = 3.8; bias = 1.28; p <.001), while inter-observer reproducibility was 86% (4.7; −.88; p <.001). There was significant association between sex and T2 relaxation times (p =.024) and significant inverse correlation between T2 relaxation times and BMI (r = −.340, p =.002). Conclusion: The assessment of T2 relaxation time measurements of sacroiliac joints seems to be highly reproducible at 1.5 T. Further studies could investigate the potential clinical application of this tool in the sacroiliac joints.

KW - Cartilage; Magnetic resonance imaging; Sacroiliac joint; T2 mapping; Adult; Feasibility Studies; Female; Healthy Volunteers; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Reproducibility of Results; Sacroiliac Joint; Radiology

KW - Nuclear Medicine and Imaging

UR - http://hdl.handle.net/10447/338423

M3 - Article

VL - 47

SP - 1691

EP - 1696

JO - Skeletal Radiology

JF - Skeletal Radiology

SN - 0364-2348

ER -