Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

1,2,3-Triazines are a class of biologically active compounds that exhibit a broad spectrum of activities, including antibacterial, antifungal, antiviral, antiproliferative, analgesic and anti-inflammatory properties. This review, which covers the literature from the end of last century to 2016, treats, through a comprehensive, systematic approach, the 1,2,3-triazine and related benzo- and hetero-fused derivatives possessing antitumor activity. Their efficacy, combined with a simple synthesis confers to these molecules a great potential as scaffold for the development of antitumor compounds.
Original languageEnglish
Pages (from-to)74-86
Number of pages13
JournalEuropean Journal of Medicinal Chemistry
Publication statusPublished - 2017

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives'. Together they form a unique fingerprint.

Cite this