Surgical pathology and the diagnosis of invasive visceral yeast infection: two case reports and literature review

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Abstract

Invasive mycoses are life-threatening opportunistic infections that have recently emerged as a cause of morbidityand mortality following general and gastrointestinal surgery.Candida species are the main fungal strains of gut flora. Gastrointestinal tract surgery might lead to mucosaldisruption and cause Candida spp. to disseminate in the bloodstream.Here we report and discuss the peculiar clinical and morphological presentation of two cases of gastrointestinalCandida albicans lesions in patients who underwent abdominal surgery.Although in the majority of cases reported in the literature, diagnosis was made on the basis of microbiologicalcriteria, we suggest that morphological features of fungi in histological sections of appropriate surgical specimenscould help to detect the degree of yeast colonization and identify patients at risk of developing severe abdominalCandida infection.Better prevention and early antifungal treatments are highlighted, and relevant scientific literature is reviewed.
Original languageEnglish
Pages (from-to)38-
Number of pages0
JournalWorld Journal of Emergency Surgery
Volume8
Publication statusPublished - 2013

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Surgical Pathology
Yeasts
Candida
Infection
Literature
Opportunistic Infections
Gastrointestinal Tract
Fungi
Mortality
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery
  • Emergency Medicine

Cite this

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title = "Surgical pathology and the diagnosis of invasive visceral yeast infection: two case reports and literature review",
abstract = "Invasive mycoses are life-threatening opportunistic infections that have recently emerged as a cause of morbidityand mortality following general and gastrointestinal surgery.Candida species are the main fungal strains of gut flora. Gastrointestinal tract surgery might lead to mucosaldisruption and cause Candida spp. to disseminate in the bloodstream.Here we report and discuss the peculiar clinical and morphological presentation of two cases of gastrointestinalCandida albicans lesions in patients who underwent abdominal surgery.Although in the majority of cases reported in the literature, diagnosis was made on the basis of microbiologicalcriteria, we suggest that morphological features of fungi in histological sections of appropriate surgical specimenscould help to detect the degree of yeast colonization and identify patients at risk of developing severe abdominalCandida infection.Better prevention and early antifungal treatments are highlighted, and relevant scientific literature is reviewed.",
keywords = "Diagnosis, Emergency Medicine, Gastrointestinal candidiasis, Surgery, Surgical pathology",
author = "Daniela Cabibi and {Di Carlo}, Paola and Salvatore Buscemi and Gaspare Gulotta and {Di Vita}, {Gaetano Giuseppe} and Giuseppe Salamone and Gianfranco Cocorullo and Francesco D'Arpa and Giuliana Guadagnino",
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T1 - Surgical pathology and the diagnosis of invasive visceral yeast infection: two case reports and literature review

AU - Cabibi, Daniela

AU - Di Carlo, Paola

AU - Buscemi, Salvatore

AU - Gulotta, Gaspare

AU - Di Vita, Gaetano Giuseppe

AU - Salamone, Giuseppe

AU - Cocorullo, Gianfranco

AU - D'Arpa, Francesco

AU - Guadagnino, Giuliana

PY - 2013

Y1 - 2013

N2 - Invasive mycoses are life-threatening opportunistic infections that have recently emerged as a cause of morbidityand mortality following general and gastrointestinal surgery.Candida species are the main fungal strains of gut flora. Gastrointestinal tract surgery might lead to mucosaldisruption and cause Candida spp. to disseminate in the bloodstream.Here we report and discuss the peculiar clinical and morphological presentation of two cases of gastrointestinalCandida albicans lesions in patients who underwent abdominal surgery.Although in the majority of cases reported in the literature, diagnosis was made on the basis of microbiologicalcriteria, we suggest that morphological features of fungi in histological sections of appropriate surgical specimenscould help to detect the degree of yeast colonization and identify patients at risk of developing severe abdominalCandida infection.Better prevention and early antifungal treatments are highlighted, and relevant scientific literature is reviewed.

AB - Invasive mycoses are life-threatening opportunistic infections that have recently emerged as a cause of morbidityand mortality following general and gastrointestinal surgery.Candida species are the main fungal strains of gut flora. Gastrointestinal tract surgery might lead to mucosaldisruption and cause Candida spp. to disseminate in the bloodstream.Here we report and discuss the peculiar clinical and morphological presentation of two cases of gastrointestinalCandida albicans lesions in patients who underwent abdominal surgery.Although in the majority of cases reported in the literature, diagnosis was made on the basis of microbiologicalcriteria, we suggest that morphological features of fungi in histological sections of appropriate surgical specimenscould help to detect the degree of yeast colonization and identify patients at risk of developing severe abdominalCandida infection.Better prevention and early antifungal treatments are highlighted, and relevant scientific literature is reviewed.

KW - Diagnosis

KW - Emergency Medicine

KW - Gastrointestinal candidiasis

KW - Surgery

KW - Surgical pathology

UR - http://hdl.handle.net/10447/84124

UR - http://www.wjes.org/content/8/1/38

M3 - Article

VL - 8

SP - 38-

JO - World Journal of Emergency Surgery

JF - World Journal of Emergency Surgery

SN - 1749-7922

ER -