Stem cell therapy: old challenges and new solutions

Carmela Rita Balistreri, Alexander Koliada, Olga Maslova, Antonella Bordin, Elena De Falco, Alexander Vaiserman

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Stem cell therapy (SCT), born as therapeutic revolution to replace pharmacological treatments, remains a hope and not yet an effective solution. Accordingly, stem cells cannot be conceivable as a “canonical” drug, because of their unique biological properties. A new reorientation in this field is emerging, based on a better understanding of stem cell biology and use of cutting-edge technologies and innovative disciplines. This will permit to solve the gaps, failures, and long-term needs, such as the retention, survival and integration of stem cells, by employing pharmacology, genetic manipulation, biological or material incorporation. Consequently, the clinical applicability of SCT for chronic human diseases will be extended, as well as its effectiveness and success, leading to long-awaited medical revolution. Here, some of these aspects are summarized, reviewing and discussing recent advances in this rapidly developing research field.
Original languageEnglish
Pages (from-to)3117-3131
Number of pages15
JournalMolecular Biology Reports
Volume47
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics

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