Two diorganotin(IV)–NANA complexes (NANA (1) = b-N-acetyl-Neuraminic Acid =5-amino-3,5-dideoxy-D-glycero-b-D-galactononulosic acid) with formula Me2Sn(IV)NANA (2) andBu2Sn(IV)NANA (3) were synthesized and characterized by 1H, 13C and 119Sn NMR spectroscopy, bothin D2O and DMSO-d6 solutions. The experimental data in DMSO suggested the monosaccharidebidentate chelation via O1 carboxylate and vicinal O2 alkoxide atoms, which, in D2O, can bedynamically extended to a third binding site (O8 atom) of the pendant chain. Coordination at the tinatom is discussed on the basis of experimental NMR data and DFT calculation.
|Number of pages||7|
|Publication status||Published - 2007|
All Science Journal Classification (ASJC) codes
- Inorganic Chemistry
Ferrante, F., Pellerito, L., Casella, G., Rotondo, E., Rotondo, A., & Bertazzi, N. (2007). Solution structure of R2Sn(IV)-β-N-Acetyl-Neuraminate (R=Me, Bu) complexes in D2O and DMSO-d6: experimental NMR and DFT computational study. Dalton Transactions, 14, 1440-1446.