Role of cachexia and fragility in the patient candidate for cardiac surgery

Carmela Rita Balistreri, Maria Cristina Foti, Calogera Pisano, Paolo Nardi, Dario Buioni, Maria Sabrina Ferrante, Claudia Altieri, Daniele Polisano, Laura Asta, Daniele Trombetti, Fabio Bertoldo, Giovanni Ruvolo, Calogero Foti

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Frailty is the major expression of accelerated aging and describes a decreased resistance to stressors, and consequently an increased vulnerability to additional diseases in elderly people. The vascular aging related to frail phenotype reflects the high susceptibility for cardiovascular diseases and negative postoperative outcomes after cardiac surgery. Sarcopenia can be considered a biological substrate of physical frailty. Malnutrition and physical inactivity play a key role in the pathogenesis of sarcopenia. We searched on Medline (PubMed) and Scopus for relevant literature published over the last 10 years and analyzed the strong correlation between frailty, sarcopenia and cardiovascular diseases in elderly patient. In our opinion, a right food intake and moderate intensity resistance exercise are mandatory in order to better prepare patients undergoing cardiac operation.
Original languageEnglish
Pages (from-to)1-17
Number of pages17
Publication statusPublished - 2021

All Science Journal Classification (ASJC) codes

  • Food Science
  • Nutrition and Dietetics


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