Risk factors for postoperative delirium after colorectal surgery for carcinoma

Gaetano Giuseppe Di Vita, Michele Saitta, Giacomo Cusumano, Giuseppe Termine, Rosalia Patti

Research output: Contribution to journalBook/Film/Article review

38 Citations (Scopus)

Abstract

Background and aimData regarding the incidence and risk factors for postoperative delirium (PD) after gastrointestinal surgery are heterogeneous because they include both benign and malignant disease. The aim of this study was to investigate the incidence and risk factors for PD in 100 consecutive patients over 65 years who underwent colorectal surgery for carcinoma.MethodsPre-operative cognitive function was assessed using the Mini Mental State Examination. The onset of PD was diagnosed by the Confusion Assessment Methods administered to the patients every 12 h starting from the first postoperative day to discharge. The severity of PD was also evaluated with the Delirium Rating Scale. Different parameters: pre-, intra- and postoperative, were analyzed. Univariate and multivariate analyses were performed.ResultsPD developed in 18% of patients. Univariate analysis revealed that advanced age, a history of PD, alcohol abuse, lower blood albumin concentration, intra-operative hypotension, elevated infusion volume and excessive blood loss were significantly related to the development of PD. On multivariate analysis, only lower levels of albumin, alcohol abuse, and hypotension were independent risk factors for PD.ConclusionsThese findings suggest that PD is a frequent complication after colorectal surgery for carcinoma. A model based on pre, intra and postoperative risk factors allows prediction of the patient’s risk for developing PD in order to implement preventive measures for this complication.
Original languageEnglish
Pages (from-to)s54-s54
Number of pages1
JournalJournal of the American College of Surgeons
Volume209
Publication statusPublished - 2009

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Colorectal Surgery
Delirium
Colorectal Neoplasms
Hypotension
Alcoholism
Albumins
Multivariate Analysis
Confusion
Incidence
Blood Volume
Cognition

All Science Journal Classification (ASJC) codes

  • Oncology(nursing)

Cite this

Risk factors for postoperative delirium after colorectal surgery for carcinoma. / Di Vita, Gaetano Giuseppe; Saitta, Michele; Cusumano, Giacomo; Termine, Giuseppe; Patti, Rosalia.

In: Journal of the American College of Surgeons, Vol. 209, 2009, p. s54-s54.

Research output: Contribution to journalBook/Film/Article review

Di Vita, Gaetano Giuseppe ; Saitta, Michele ; Cusumano, Giacomo ; Termine, Giuseppe ; Patti, Rosalia. / Risk factors for postoperative delirium after colorectal surgery for carcinoma. In: Journal of the American College of Surgeons. 2009 ; Vol. 209. pp. s54-s54.
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abstract = "Background and aimData regarding the incidence and risk factors for postoperative delirium (PD) after gastrointestinal surgery are heterogeneous because they include both benign and malignant disease. The aim of this study was to investigate the incidence and risk factors for PD in 100 consecutive patients over 65 years who underwent colorectal surgery for carcinoma.MethodsPre-operative cognitive function was assessed using the Mini Mental State Examination. The onset of PD was diagnosed by the Confusion Assessment Methods administered to the patients every 12 h starting from the first postoperative day to discharge. The severity of PD was also evaluated with the Delirium Rating Scale. Different parameters: pre-, intra- and postoperative, were analyzed. Univariate and multivariate analyses were performed.ResultsPD developed in 18{\%} of patients. Univariate analysis revealed that advanced age, a history of PD, alcohol abuse, lower blood albumin concentration, intra-operative hypotension, elevated infusion volume and excessive blood loss were significantly related to the development of PD. On multivariate analysis, only lower levels of albumin, alcohol abuse, and hypotension were independent risk factors for PD.ConclusionsThese findings suggest that PD is a frequent complication after colorectal surgery for carcinoma. A model based on pre, intra and postoperative risk factors allows prediction of the patient’s risk for developing PD in order to implement preventive measures for this complication.",
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T1 - Risk factors for postoperative delirium after colorectal surgery for carcinoma

AU - Di Vita, Gaetano Giuseppe

AU - Saitta, Michele

AU - Cusumano, Giacomo

AU - Termine, Giuseppe

AU - Patti, Rosalia

PY - 2009

Y1 - 2009

N2 - Background and aimData regarding the incidence and risk factors for postoperative delirium (PD) after gastrointestinal surgery are heterogeneous because they include both benign and malignant disease. The aim of this study was to investigate the incidence and risk factors for PD in 100 consecutive patients over 65 years who underwent colorectal surgery for carcinoma.MethodsPre-operative cognitive function was assessed using the Mini Mental State Examination. The onset of PD was diagnosed by the Confusion Assessment Methods administered to the patients every 12 h starting from the first postoperative day to discharge. The severity of PD was also evaluated with the Delirium Rating Scale. Different parameters: pre-, intra- and postoperative, were analyzed. Univariate and multivariate analyses were performed.ResultsPD developed in 18% of patients. Univariate analysis revealed that advanced age, a history of PD, alcohol abuse, lower blood albumin concentration, intra-operative hypotension, elevated infusion volume and excessive blood loss were significantly related to the development of PD. On multivariate analysis, only lower levels of albumin, alcohol abuse, and hypotension were independent risk factors for PD.ConclusionsThese findings suggest that PD is a frequent complication after colorectal surgery for carcinoma. A model based on pre, intra and postoperative risk factors allows prediction of the patient’s risk for developing PD in order to implement preventive measures for this complication.

AB - Background and aimData regarding the incidence and risk factors for postoperative delirium (PD) after gastrointestinal surgery are heterogeneous because they include both benign and malignant disease. The aim of this study was to investigate the incidence and risk factors for PD in 100 consecutive patients over 65 years who underwent colorectal surgery for carcinoma.MethodsPre-operative cognitive function was assessed using the Mini Mental State Examination. The onset of PD was diagnosed by the Confusion Assessment Methods administered to the patients every 12 h starting from the first postoperative day to discharge. The severity of PD was also evaluated with the Delirium Rating Scale. Different parameters: pre-, intra- and postoperative, were analyzed. Univariate and multivariate analyses were performed.ResultsPD developed in 18% of patients. Univariate analysis revealed that advanced age, a history of PD, alcohol abuse, lower blood albumin concentration, intra-operative hypotension, elevated infusion volume and excessive blood loss were significantly related to the development of PD. On multivariate analysis, only lower levels of albumin, alcohol abuse, and hypotension were independent risk factors for PD.ConclusionsThese findings suggest that PD is a frequent complication after colorectal surgery for carcinoma. A model based on pre, intra and postoperative risk factors allows prediction of the patient’s risk for developing PD in order to implement preventive measures for this complication.

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KW - postoperative delirium

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JO - Journal of the American College of Surgeons

JF - Journal of the American College of Surgeons

SN - 1072-7515

ER -