We describe a patient with frontotemporaldementia (FTD), a tauopathy, who also showed clinical and polysomnographic features of REM sleep behavior disorder (RBD). The patient is a 78-year-old male with a 1 year history of behavioral dysfunction involving emotion,character and social functioning. Brain imaging and the results of neuropsychological testing were consistent with a diagnosis of FTD. Sleep symptom onset occurred someyears before the behavioral changes, and consisted of unpleasant dreams, vocalization, and prominent motor behaviors. A polysomnography confirmed the diagnosis ofRBD. Our findings support the hypothesis that RBD, although more frequent in synucleinopathies, might be a pathological stage in the development of almost everyneurodegenerative disorder in which the pathological process involves the cerebral structures that regulate muscle tone during REM sleep
|Number of pages||3|
|Publication status||Published - 2011|
All Science Journal Classification (ASJC) codes
- Clinical Neurology
- Psychiatry and Mental health
Realmuto, S., Cannizzaro, E., Cupidi, C., Mattaliano, A., Lo Coco, D., Lo Coco, D., & Baiamonte, V. (2011). REM sleep behavior disorder in a patient with frontotemporal dementia. Neurological Sciences, 33, 371-373.