REM sleep behavior disorder in a patient with frontotemporal dementia

Sabrina Realmuto, Emanuele Cannizzaro, Chiara Cupidi, Alfredo Mattaliano, Daniele Lo Coco, Daniele Lo Coco, Valentina Baiamonte

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15 Citations (Scopus)


We describe a patient with frontotemporaldementia (FTD), a tauopathy, who also showed clinical and polysomnographic features of REM sleep behavior disorder (RBD). The patient is a 78-year-old male with a 1 year history of behavioral dysfunction involving emotion,character and social functioning. Brain imaging and the results of neuropsychological testing were consistent with a diagnosis of FTD. Sleep symptom onset occurred someyears before the behavioral changes, and consisted of unpleasant dreams, vocalization, and prominent motor behaviors. A polysomnography confirmed the diagnosis ofRBD. Our findings support the hypothesis that RBD, although more frequent in synucleinopathies, might be a pathological stage in the development of almost everyneurodegenerative disorder in which the pathological process involves the cerebral structures that regulate muscle tone during REM sleep
Original languageEnglish
Pages (from-to)371-373
Number of pages3
JournalNeurological Sciences
Publication statusPublished - 2011


All Science Journal Classification (ASJC) codes

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

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