Relationship between circulating E-selectin, DD genotype of angiotensin-converting-enzyme, and cardiovascular damage in central obese subjects

Giovanni Triolo, Antonio Pinto, Anna Licata, Giuseppe Licata, Gaspare Parrinello, Tiziana Di Chiara, Rosario Scaglione, Salvatore Corrao, Giuseppe Licata, Antonio Pinto, Giovanni Triolo, Anna Licata, Christiano Argano, Tiziana Di Chiara, Giovanni Duro, Salvatore Corrao, Gaspare Parrinello, Rosario Scaglione

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Fifty-six young central obese patients were investigated to evaluate relationships between soluble E-selectin (sE-S), angiotensin-converting enzyme (ACE) gene polymorphism, left ventricular function and structure, and carotid morphology by determination of sE-S and ACE genotypes. Our results indicated that central obese subjects with concomitant higher levels of sE-S and ACE DD genotype may be characterized by early cardiovascular alterations and then considered a particular subset of subjects at higher risk of cardiovascular disease.
Original languageEnglish
Pages (from-to)999-1004
Number of pages6
JournalMETABOLISM, CLINICAL AND EXPERIMENTAL
Volume52
Publication statusPublished - 2003

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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