Recurrent leishmaniasis in kidney transplant recipients: Report of 2 cases and systematic review of the literature

Antonio Cascio; null Nilufer Broeders; null Simon; Mario Corbellino; null Wissing; null Del Marmol; null Remmelink; null Antinori; null Cascio; null Abramowicz; null Nortier

Recurrent leishmaniasis in kidney transplant recipients: Report of 2 cases and systematic review of the literature

Antonio Cascio, Nilufer Broeders, Simon, Mario Corbellino, Wissing, Del Marmol, Remmelink, Antinori, Cascio, Abramowicz, Nortier

Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza “G. D’Alessandro”

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed. © 2011 John Wiley & Sons A/S.

Original language	English
Pages (from-to)	397-406
Number of pages	10
Journal	Transplant Infectious Disease
Volume	13
Publication status	Published - 2011

All Science Journal Classification (ASJC) codes

Infectious Diseases
Transplantation

Cite this

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title = "Recurrent leishmaniasis in kidney transplant recipients: Report of 2 cases and systematic review of the literature",

abstract = "The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed. {\textcopyright} 2011 John Wiley & Sons A/S.",

author = "Antonio Cascio and {Nilufer Broeders} and Simon and Mario Corbellino and Wissing and {Del Marmol} and Remmelink and Antinori and Cascio and Abramowicz and Nortier",

year = "2011",

language = "English",

volume = "13",

pages = "397--406",

journal = "Transplant Infectious Disease",

issn = "1398-2273",

publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Recurrent leishmaniasis in kidney transplant recipients: Report of 2 cases and systematic review of the literature

AU - Cascio, Antonio

AU - Nilufer Broeders, null

AU - Simon, null

AU - Corbellino, Mario

AU - Wissing, null

AU - Del Marmol, null

AU - Remmelink, null

AU - Antinori, null

AU - Cascio, null

AU - Abramowicz, null

AU - Nortier, null

PY - 2011

Y1 - 2011

N2 - The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed. © 2011 John Wiley & Sons A/S.

AB - The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed. © 2011 John Wiley & Sons A/S.

UR - http://hdl.handle.net/10447/160432

M3 - Article

SN - 1398-2273

VL - 13

SP - 397

EP - 406

JO - Transplant Infectious Disease

JF - Transplant Infectious Disease

ER -

Recurrent leishmaniasis in kidney transplant recipients: Report of 2 cases and systematic review of the literature

Abstract

All Science Journal Classification (ASJC) codes

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