Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle

Gabriella Cancemi, Maria Valeria Raimondi, Benedetta Maggio, Stella Maria Cascioferro, Giuseppe Daidone, Demetrio Raffa, Fabiana Plescia, Gabriella Cancemi, Fabiana Plescia, Fabiana Plescia, Stella Cascioferro, Demetrio Raffa, Giuseppe Daidone, Maria Valeria Raimondi, Benedetta Maggio

Research output: Contribution to journalArticlepeer-review

63 Citations (Scopus)

Abstract

In this review we report the recent advances in bioactive system containing pyrazole fused with a five membered heterocycle, covering the time span of the last decade. All of them are represented around the common structure of the pyrazole ring fused with another five membered heterocycle containing the nitrogen, sulfur and oxygen atoms in all their possible combinations. The classification we have used is based in terms of the therapeutic area providing, when possible, some general conclusions on the targets and mechanisms of action as well as the structure-activity relationships of the molecules.
Original languageEnglish
Pages (from-to)732-746
Number of pages15
JournalEuropean Journal of Medicinal Chemistry
Volume97
Publication statusPublished - 2015

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

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