PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients

Rosalinda Allegro, Darvinio Melloni, Anna Martorana, Vincenzo Serretta, Rosalinda Allegro, Angela Catanese, Raimondo Liotta

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Microscopic foci of prostatitis may induce prostate-specific antigen (PSA) increase. PSA reduction after antibiotics might identify those patients in whom biopsy can be avoided. Ninety-nine patients received ciprofloxacin for 3 weeks, of whom 59 showed PSA reduction. Histology detected small foci of prostatitis in 65% of cases. Carcinoma was found in 40 and 20.3% of patients with unchanged or decreased PSA, respectively (P=0.03). No cancer was detected if PSA decreased below 4 ng/ml or more than 70%. Biopsy can be postponed, with a low risk of missing a cancer, if PSA decreases more than 70% or below 4 ng/ml.
Original languageEnglish
Pages (from-to)148-152
Number of pages5
JournalProstate Cancer and Prostatic Diseases
Volume11
Publication statusPublished - 2008

All Science Journal Classification (ASJC) codes

  • Oncology
  • Urology
  • Cancer Research

Fingerprint Dive into the research topics of 'PSA reduction (after antibiotics) permits to avoid or postpone prostate biopsy in selected patients'. Together they form a unique fingerprint.

  • Cite this