Propagation pattern analysis during atrial fibrillation based on sparse modeling

Luca Faes, Ulrike Richter, Luca Faes, Leif Sornmo, Flavia Ravelli

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

In this study, sparse modeling is introduced for the estimation of propagation patterns in intracardiac atrial fibrillation (AF) signals. The estimation is based on the partial directed coherence function, derived from fitting a multivariate autoregressive model to the observed signal using least-squares (LS) estimation. The propagation pattern analysis incorporates prior information on sparse coupling as well as the distance between the recording sites. Two optimization methods are employed for estimation of the model parameters, namely, the adaptive group least absolute selection and shrinkage operator (aLASSO), and a novel method named the distance-adaptive group LASSO (dLASSO). Using simulated data, both optimization methods were superior to LS estimation with respect to detection and estimation performance. The normalized error between the true and estimated model parameters dropped from 0.20±; 0.04 for LS estimation to 0.03 ± 0.01 for both aLASSO and dLASSO when the number of available data samples exceeded the number of model parameters by a factor of 5. For shorter data segments, the error reduction was more pronounced and information on the distance gained in importance. Propagation pattern analysis was also studied on intracardiac AF data, the results showing that the identification of propagation patterns is substantially simplified by the sparsity assumption. © 1964-2012 IEEE.
Original languageEnglish
Pages (from-to)1319-1328
Number of pages10
JournalIEEE Transactions on Biomedical Engineering
Volume59
Publication statusPublished - 2012

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

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