Prognostic value of IL-6 and IL-10 serum levels and immunonutrional assessment in determining postoperative complications after geriatric surgery

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Abstract

The onset of postoperative septic complications hasrecently been associated to serum levels of interleukin (IL)IL-6 and IL-10. Patients with complications have higherserum levels than patients without complication after surgery.IL-6 has been recognized as early marker of postoperativeseptic events. Furthermore IL-6 increases with age,expecially if there are associated diseases. It is a sign offunctional deterioration of different organs.The disregulation in interleukin production, anestheticdrugs, hemorrhage and transfusions may lead to the onsetof postoperative complications. The latter are more frequentin oncologic patients.The aim of our study is to evaluate pre- and postoperativeprofile of some inflammatory markers (IL-6, IL-10 and Creactiveprotein CRP) and immunonutritional assessment(through albumin serum levels and lymphocyte count) ina group of elderly patients undergone to major intrabdominalsurgery. We related the data obtained to theonset of postoperative complications.
Original languageEnglish
Pages (from-to)1-2
Number of pages2
JournalBMC Geriatrics
VolumeA92
Publication statusPublished - 2009

All Science Journal Classification (ASJC) codes

  • Geriatrics and Gerontology

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