[automatically translated] Melanogenesis process in the treatment of hyperpigmentation: physiology and treatment Matteo Tutino, Joseph Morici, L. Cavarra, Francesco Nanfitò, D. Camacaro, Vittorio Calabrese. University of Palermo, Department of Experimental Biomedicine and Clinical Neurosciences - University of Catania, Clinical Biochemistry Department Melanogenesis is the process by which it is produced melanin, the pigment giving to the skin. Responsible for the production of melanin is the melanocyte. However, it is possible to speak of a real unit cheratinocita- melanocyte. In fact both of these cells are activated as a result of aggression of any kind in which the skin is subjected. Following fact of exposure to UVB but also UVA, to mechanical or thermal insults, these cells become activated and communicate with each other through a complex network of cellular mediators. To determine the hyperpigmentation is an abnormal cellular response to these stimuli with a communication mechanism melanocyte-keratinocyte altered. In this relationship it develops in detail the pathophysiological process by evaluating which treatment results in the restoration of normal cellular activity by preventing and treating hyperpigmentation as well.
|Number of pages||1|
|Publication status||Published - 2012|